Trauma-induced coagulopathy

EE Moore, HB Moore, LZ Kornblith, MD Neal… - Nature Reviews …, 2021‏ - nature.com
Uncontrolled haemorrhage is a major preventable cause of death in patients with traumatic
injury. Trauma-induced coagulopathy (TIC) describes abnormal coagulation processes that …

Thromboelastography (TEG) or thromboelastometry (ROTEM) to monitor haemostatic treatment versus usual care in adults or children with bleeding

A Wikkelsø, J Wetterslev, AM Møller… - Cochrane Database of …, 2016‏ - cochranelibrary.com
Background Severe bleeding and coagulopathy are serious clinical conditions that are
associated with high mortality. Thromboelastography (TEG) and thromboelastometry …

The European guideline on management of major bleeding and coagulopathy following trauma

DR Spahn, B Bouillon, V Cerny, J Duranteau… - Critical care, 2019‏ - Springer
Background Severe traumatic injury continues to present challenges to healthcare systems
around the world, and post-traumatic bleeding remains a leading cause of potentially …

The European guideline on management of major bleeding and coagulopathy following trauma

R Rossaint, B Bouillon, V Cerny, TJ Coats, J Duranteau… - Critical care, 2016‏ - Springer
Background Severe trauma continues to represent a global public health issue and mortality
and morbidity in trauma patients remains substantial. A number of initiatives have aimed to …

Management of bleeding and coagulopathy following major trauma: an updated European guideline

DR Spahn, B Bouillon, V Cerny, TJ Coats, J Duranteau… - Critical care, 2013‏ - Springer
Introduction Evidence-based recommendations are needed to guide the acute management
of the bleeding trauma patient. When these recommendations are implemented patient …

[PDF][PDF] Tranexamic acid: a clinical review

W Ng, A Jerath, M Wąsowicz - Anestezjologia Intensywna Terapia, 2015‏ - termedia.pl
Blood loss and subsequent transfusions are associated with major morbidity and mortality.
The use of antifibrinolytics can reduce blood loss in cardiac surgery, trauma, orthopedic …

Point‐of‐care testing in haemostasis

DJ Perry, DA Fitzmaurice, S Kitchen… - British Journal of …, 2010‏ - Wiley Online Library
Point‐of‐care testing (POCT) in haematology has seen a significant increase in both the
spectrum of tests available and the number of tests performed annually. POCT is frequently …

[HTML][HTML] Viscoelastic point-of-care testing to assist with the diagnosis, management and monitoring of haemostasis: a systematic review and cost-effectiveness …

P Whiting, M Al, M Westwood, IC Ramos… - Health technology …, 2015‏ - pmc.ncbi.nlm.nih.gov
BACKGROUND Patients with substantive bleeding usually require transfusion and/or (re-)
operation. Red blood cell (RBC) transfusion is independently associated with a greater risk …

[HTML][HTML] The incidence and magnitude of fibrinolytic activation in trauma patients

I Raza, R Davenport, C Rourke, S Platton… - Journal of Thrombosis …, 2013‏ - Elsevier
Background: Trauma is a global disease, with over 2.5 million deaths annually from
hemorrhage and coagulopathy. Overt hyperfibrinolysis is rare in trauma, and is associated …

Effect of thromboelastography (TEG®) and rotational thromboelastometry (ROTEM®) on diagnosis of coagulopathy, transfusion guidance and mortality in trauma …

LT Da Luz, B Nascimento, AK Shankarakutty, S Rizoli… - Critical Care, 2014‏ - Springer
Introduction The understanding of coagulopathies in trauma has increased interest in
thromboelastography (TEG®) and thromboelastometry (ROTEM®), which promptly evaluate …