Advances in molecular and imaging biomarkers in lower-grade gliomas

A Picca, F Bruno, L Nichelli, M Sanson… - Expert Review of …, 2023 - Taylor & Francis
ABSTRACT Introduction Lower-grade (grade 2–3) gliomas (LGGs) constitutes a group of
primary brain tumors with variable clinical behaviors and treatment responses. Recent …

[HTML][HTML] The promise of metabolic imaging in diffuse midline glioma

S Lovibond, AN Gewirtz, L Pasquini, S Krebs… - Neoplasia, 2023 - Elsevier
Recent insights into histopathological and molecular subgroups of glioma have
revolutionized the field of neuro-oncology by refining diagnostic categories. An emblematic …

The T2-FLAIR mismatch sign in oncologic neuroradiology: History, current use, emerging data, and future directions

SA Dagher, RH Lochner, BB Ozkara… - The Neuroradiology …, 2024 - journals.sagepub.com
The T2-Fluid-Attenuated Inversion Recovery (T2-FLAIR) mismatch sign is a radiogenomic
marker that is easily discernible on preoperative conventional MR imaging. Application of …

Dynamic contrast‐enhanced MRI parameters and normalized ADC values could aid differentiation of skull base osteomyelitis from nasopharyngeal cancer

A Baba, R Kurokawa, M Kurokawa… - American Journal …, 2023 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The skull base osteomyelitis sometimes can be difficult to
distinguish from nasopharyngeal cancer. This study aimed to investigate the differences …

Distinct MRI characteristics of spinal cord diffuse midline glioma, H3 K27-altered in comparison to spinal cord glioma without H3 K27-alteration and demyelination …

Y Ying, X Liu, X Li, N Mei, Z Ruan, Y Lu… - Acta …, 2024 - journals.sagepub.com
Background An applicable magnetic resonance imaging (MRI) biomarker for diffuse midline
glioma (DMG), H3 K27-altered of the spinal cord is important for non-invasive diagnosis …

Development and validation of a machine learning algorithm for predicting diffuse midline glioma, H3 K27–altered, H3 K27 wild-type high-grade glioma, and primary …

K Lv, H Chen, X Cao, P Du, J Chen, X Liu, L Zhu… - Journal of …, 2022 - thejns.org
OBJECTIVE Preoperative diagnosis of diffuse midline glioma, H3 K27–altered (DMG-A) and
midline high-grade glioma without H3 K27 alteration (DMG-W), as well as midline primary …

Neuroimaging features of FOXR2‐activated CNS neuroblastoma: A case series and systematic review

K Shimazaki, R Kurokawa, A Franson… - Journal of …, 2023 - Wiley Online Library
Background and Purpose CNS neuroblastoma, FOXR2‐activated (CNS NB‐FOXR2) is a
newly recognized tumor type in the 2021 World Health Organization classification of central …

Differentiation of pilocytic astrocytoma, medulloblastoma, and hemangioblastoma on diffusion-weighted and dynamic susceptibility contrast perfusion MRI

R Kurokawa, M Kurokawa, A Baba, J Kim… - Medicine, 2022 - journals.lww.com
This study aimed to evaluate the diagnostic performance of dynamic susceptibility contrast
(DSC) perfusion magnetic resonance imaging and apparent diffusion coefficient (ADC) for …

Imaging Genomics of Glioma Revisited: Analytic Methods to Understand Spatial and Temporal Heterogeneity

CN Kersch, M Kim, J Stoller… - American Journal of …, 2024 - Am Soc Neuroradiology
An improved understanding of the cellular and molecular biologic processes responsible for
brain tumor development, growth, and resistance to therapy is fundamental to improving …

[HTML][HTML] H3 K27-altered diffuse midline glioma in adults arising from atypical regions: Two case reports and literature review

N Sugii, Y Ninomiya, Y Akimoto, T Tsurubuchi… - Radiology Case …, 2024 - Elsevier
Diffuse midline glioma (DMG), H3 K27-altered, is a newly defined “pediatric-type,” diffuse,
high-grade glioma under current WHO classifications (updated in 2021). An essential …