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Post-transcriptional control of miRNA biogenesis
MicroRNAs (miRNAs) are important regulators of gene expression that bind complementary
target mRNAs and repress their expression. Precursor miRNA molecules undergo nuclear …
target mRNAs and repress their expression. Precursor miRNA molecules undergo nuclear …
Classical and noncanonical functions of miRNAs in cancers
Alterations in microRNAs (miRNAs) expression are causative in the initiation and
progression of human cancers. The molecular events responsible for the widespread …
progression of human cancers. The molecular events responsible for the widespread …
RNA-binding proteins in cancer: old players and new actors
RNA-binding proteins (RBPs) are key players in post-transcriptional events. The
combination of versatility of their RNA-binding domains with structural flexibility enables …
combination of versatility of their RNA-binding domains with structural flexibility enables …
A network-biology perspective of microRNA function and dysfunction in cancer
MicroRNAs (miRNAs) participate in most aspects of cellular differentiation and homeostasis,
and consequently have roles in many pathologies, including cancer. These small non …
and consequently have roles in many pathologies, including cancer. These small non …
MicroRNA biogenesis pathways in cancer
S Lin, RI Gregory - Nature reviews cancer, 2015 - nature.com
MicroRNAs (miRNAs) are critical regulators of gene expression. Amplification and
overexpression of individual'oncomiRs' or genetic loss of tumour suppressor miRNAs are …
overexpression of individual'oncomiRs' or genetic loss of tumour suppressor miRNAs are …
[HTML][HTML] The roles of the Let-7 family of MicroRNAs in the regulation of cancer stemness
Y Ma, N Shen, MS Wicha, M Luo - Cells, 2021 - mdpi.com
Cancer has long been viewed as a disease of normal development gone awry. Cancer stem-
like cells (CSCs), also termed as tumor-initiating cells (TICs), are increasingly recognized as …
like cells (CSCs), also termed as tumor-initiating cells (TICs), are increasingly recognized as …
Cancer stem cells: A review from origin to therapeutic implications
Cancer stem cells (CSCs), also known as tumor‐initiating cells (TICs), are elucidated as
cells that can perpetuate themselves via autorestoration. These cells are highly resistant to …
cells that can perpetuate themselves via autorestoration. These cells are highly resistant to …
The emerging roles of YAP and TAZ in cancer
Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ)
are the major downstream effectors of the Hippo pathway, which regulates tissue …
are the major downstream effectors of the Hippo pathway, which regulates tissue …
Micro-RNA: The darkhorse of cancer
The discovery of micro RNAs (miRNA) in cancer has opened up new vistas for researchers
in recent years. Micro RNAs area set of small, endogenous, highly conserved, non-coding …
in recent years. Micro RNAs area set of small, endogenous, highly conserved, non-coding …
Tumor suppressor miRNA in cancer cells and the tumor microenvironment: mechanism of deregulation and clinical implications
K Otmani, P Lewalle - Frontiers in oncology, 2021 - frontiersin.org
MicroRNAs (miRNAs) are noncoding RNAs that have been identified as important
posttranscriptional regulators of gene expression. miRNAs production is controlled at …
posttranscriptional regulators of gene expression. miRNAs production is controlled at …