Physiology of astroglia

A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

Extracellular vesicle-mediated cell–cell communication in the nervous system: Focus on neurological diseases

C Caruso Bavisotto, F Scalia… - International journal of …, 2019 - mdpi.com
Extracellular vesicles (EVs), including exosomes, are membranous particles released by
cells into the extracellular space. They are involved in cell differentiation, tissue …

Neurons diversify astrocytes in the adult brain through sonic hedgehog signaling

WT Farmer, T Abrahamsson, S Chierzi, C Lui… - Science, 2016 - science.org
Astrocytes are specialized and heterogeneous cells that contribute to central nervous
system function and homeostasis. However, the mechanisms that create and maintain …

Origin, lineage and function of cerebellar glia

A Buffo, F Rossi - Progress in neurobiology, 2013 - Elsevier
The glial cells of the cerebellum, and particularly astrocytes and oligodendrocytes, are
characterized by a remarkable phenotypic variety, in which highly peculiar morphological …

Glial connexins and pannexins in the healthy and diseased brain

C Giaume, CC Naus, JC Sáez… - Physiological …, 2021 - journals.physiology.org
Over the past several decades a large amount of data have established that glial cells, the
main cell population in the brain, dynamically interact with neurons and thus impact their …

ATP: a ubiquitous gliotransmitter integrating neuron–glial networks

AM Butt - Seminars in cell & developmental biology, 2011 - Elsevier
Astrocytes are ideally situated to integrate glial and neuronal functions and neurovascular
coupling by way of their multiple contacts with neurons, glia and blood vessels. There is a …

The homeostatic astroglia emerges from evolutionary specialization of neural cells

A Verkhratsky, M Nedergaard - … Transactions of the …, 2016 - royalsocietypublishing.org
Evolution of the nervous system progressed through cellular diversification and
specialization of functions. Conceptually, the nervous system is composed from electrically …

Developmental origins of astrocyte heterogeneity: the final frontier of CNS development

LS Chaboub, B Deneen - Developmental neuroscience, 2013 - karger.com
Astrocytes are the most abundant cell type in the central nervous system, have diverse
physiological roles in both health and disease, and exhibit phenotypic heterogeneity. In …

Astrocytes: heterogeneous and dynamic phenotypes in neurodegeneration and innate immunity

C Cunningham, A Dunne… - The …, 2019 - journals.sagepub.com
Astrocytes are the most numerous cell type in the brain and perform several essential
functions in supporting neuronal metabolism and actively participating in neural circuit and …

[HTML][HTML] Region-specific characteristics of astrocytes and microglia: a possible involvement in aging and diseases

J Lee, SW Kim, KT Kim - Cells, 2022 - mdpi.com
Although different regions of the brain are dedicated to specific functions, the intra-and inter-
regional heterogeneity of astrocytes and microglia in these regions has not yet been fully …