NF-κB signaling in gastric cancer

O Sokolova, M Naumann - Toxins, 2017 - mdpi.com
Gastric cancer is a leading cause of cancer death worldwide. Diet, obesity, smoking and
chronic infections, especially with Helicobacter pylori, contribute to stomach cancer …

HER2 heterogeneity in gastric/gastroesophageal cancers: from benchside to practice

F Grillo, M Fassan, F Sarocchi… - World journal of …, 2016 - pmc.ncbi.nlm.nih.gov
HER2 is overexpressed in approximately 10%-20% of gastric and gastroesophageal
junction carcinomas. In these types of cancer, accurate assessment of HER2 status is …

[HTML][HTML] A phase I dose-escalation study of IMAB362 (Zolbetuximab) in patients with advanced gastric and gastro-oesophageal junction cancer

U Sahin, M Schuler, H Richly, S Bauer, A Krilova… - European Journal of …, 2018 - Elsevier
Introduction IMAB362 (Zolbetuximab) is a chimeric monoclonal antibody that binds to
Claudin-18.2, a target antigen specific to cancer cells. In vitro, IMAB362 mediates cell death …

[HTML][HTML] Perioperative treatment in resectable gastric cancer: current perspectives and future directions

A Petrillo, L Pompella, G Tirino, A Pappalardo… - Cancers, 2019 - mdpi.com
Gastric cancer (GC) is the fifth-most common cancer worldwide and an important cause of
cancer-related-death. The growing knowledge of its molecular pathogenesis has shown that …

FGFR pathway inhibition in gastric cancer: The golden era of an old target?

CG Lengyel, S Hussain, A Seeber… - Life, 2022 - mdpi.com
Gastric cancer (GC) is the third leading cause of cancer-associated death worldwide. The
majority of patients are diagnosed at an advanced/metastatic stage of disease due to a lack …

[HTML][HTML] CircRNAs as potential blood biomarkers and key elements in regulatory networks in gastric cancer

L Reis-das-Mercês, T Vinasco-Sandoval… - International Journal of …, 2022 - mdpi.com
Gastric cancer (GC) is the fifth most common type of cancer and the third leading cause of
cancer death in the world. It is a disease that encompasses a variety of molecular …

Genomic alterations in BCL2L1 and DLC1 contribute to drug sensitivity in gastric cancer

H Park, SY Cho, H Kim, D Na, JY Han, J Chae… - Proceedings of the …, 2015 - pnas.org
Gastric cancer (GC) is the third leading cause of cancer-related deaths worldwide. Recent
high-throughput analyses of genomic alterations revealed several driver genes and altered …

Gastric cancer: current and evolving treatment landscape

W Sun, L Yan - Chinese journal of cancer, 2016 - Springer
Gastric (including gastroesophageal junction) cancer is the third leading cause of cancer-
related death in the world. In China, an estimated 420,000 patients were diagnosed with …

Efficacy and safety for Apatinib treatment in advanced gastric cancer: a real world study

Y Zhang, C Han, J Li, L Zhang, L Wang, S Ye, Y Hu… - Scientific reports, 2017 - nature.com
Apatinib has been proved to be effective and safe among patients in gastric cancer in Phase
II and III Trials. We aimed to evaluate its efficacy and safety in real world practice, and to …

Large scale, multicenter, prospective study of apatinib in advanced gastric cancer: a real-world study from China

W Peng, F Zhang, Z Wang, D Li, Y He… - Cancer Management …, 2020 - Taylor & Francis
Background In China, gastric cancer (GC) ranks second in incidence and mortality. Over
80% of patients with GC were diagnosed at an advanced stage with poor clinical outcome …