Preeclampsia: risk factors, diagnosis, management, and the cardiovascular impact on the offspring

R Fox, J Kitt, P Leeson, CYL Aye… - Journal of clinical …, 2019 - mdpi.com
Hypertensive disorders of pregnancy affect up to 10% of pregnancies worldwide, which
includes the 3%–5% of all pregnancies complicated by preeclampsia. Preeclampsia is …

[HTML][HTML] Role of oxidative stress in the dysfunction of the placental endothelial nitric oxide synthase in preeclampsia

P Guerby, O Tasta, A Swiader, F Pont, E Bujold… - Redox biology, 2021 - Elsevier
Preeclampsia (PE) is a multifactorial pregnancy disease, characterized by new-onset
gestational hypertension with (or without) proteinuria or end-organ failure, exclusively …

Association between gut microbiota and preeclampsia-eclampsia: a two-sample Mendelian randomization study

P Li, H Wang, L Guo, X Gou, G Chen, D Lin, D Fan… - BMC medicine, 2022 - Springer
Background Several recent observational studies have reported that gut microbiota
composition is associated with preeclampsia. However, the causal effect of gut microbiota …

Early prediction of preeclampsia in pregnancy with cell-free RNA

MN Moufarrej, SK Vorperian, RJ Wong, AA Campos… - Nature, 2022 - nature.com
Liquid biopsies that measure circulating cell-free RNA (cfRNA) offer an opportunity to study
the development of pregnancy-related complications in a non-invasive manner and to …

First trimester preeclampsia screening and prediction

P Chaemsaithong, DS Sahota, LC Poon - American journal of obstetrics …, 2022 - Elsevier
Preeclampsia is a major cause of maternal and perinatal morbidity and mortality. Early-onset
disease requiring preterm delivery is associated with a higher risk of complications in both …

Gut dysbiosis promotes preeclampsia by regulating macrophages and trophoblasts

J **, L Gao, X Zou, Y Zhang, Z Zheng… - Circulation …, 2022 - Am Heart Assoc
Background: Preeclampsia is one of the leading causes of maternal and perinatal morbidity
and is characterized by hypertension, inflammation, and placental dysfunction. Gut …

The angiotensin AT2 receptor: from a binding site to a novel therapeutic target

UM Steckelings, RE Widdop, ED Sturrock… - Pharmacological …, 2022 - Elsevier
Discovered more than 30 years ago, the angiotensin AT 2 receptor (AT 2 R) has evolved
from a binding site with unknown function to a firmly established major effector within the …

Preeclampsia: maternal systemic vascular disorder caused by generalized endothelial dysfunction due to placental antiangiogenic factors

T Tomimatsu, K Mimura, S Matsuzaki, M Endo… - International journal of …, 2019 - mdpi.com
Preeclampsia, a systemic vascular disorder characterized by new-onset hypertension and
proteinuria after 20 weeks of gestation, is the leading cause of maternal and perinatal …

[HTML][HTML] Preeclampsia

SA Karrar, DJ Martingano, PL Hong - StatPearls [Internet], 2024 - ncbi.nlm.nih.gov
Objectives: Identify the criteria for preeclampsia with and without severe features.
Differentiate between the different hypertensive disorders of pregnancy. Assess screening …

Preeclampsia pathophysiology and adverse outcomes during pregnancy and postpartum

C Bisson, S Dautel, E Patel, S Suresh, P Dauer… - Frontiers in …, 2023 - frontiersin.org
Background Preeclampsia is a disease with far-reaching consequences that extend beyond
the immediate postpartum period and have a significant impact later in life. Preeclampsia …