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In-silico modelling of the mitogen-activated protein kinase (MAPK) pathway in colorectal cancer: mutations and targeted therapy
Introduction: Chemical reaction networks (CRNs) are powerful tools for describing the
complex nature of cancer's onset, progression, and therapy. The main reason for their …
complex nature of cancer's onset, progression, and therapy. The main reason for their …
In-silico modelling of the mitogen-activated kinase (MAPK) pathway in colorectal cancer: mutations and targeted therapy
Chemical reaction networks are powerful tools for computing the complex nature of cancer's
onset, progression, and therapy. The main reason for their effectiveness is in the fact that …
onset, progression, and therapy. The main reason for their effectiveness is in the fact that …
[PDF][PDF] A Computational Tool For Sensitivity Analysis in Chemical Reaction Networks Modeling Cancer Cell Signaling
A CRN can be modeled through a system of ODE:{x (t)= Sv (x (t), k 0) x (0)= x0 where▶ x
(t)=(x1 (t),..., xn (t)) T: chemical species concentrations▶ k 0=(k 0 1,..., k 0 r) T: reaction rate …
(t)=(x1 (t),..., xn (t)) T: chemical species concentrations▶ k 0=(k 0 1,..., k 0 r) T: reaction rate …
An efficient Newton-based approach for computing steady states of chemical reaction networks modelling cancer cells
S Berraa, S Sommarivaa, F Benvenutoa, G Cavigliaa… - PROCEEDINGS OF SIMAI … - unibas.it
From a mathematical viewpoint, CRNs can be modelled as systems of autonomous ordinary
differential equations, whose steady state solutions yield the cells proteins concentrations at …
differential equations, whose steady state solutions yield the cells proteins concentrations at …