On the Effect of Liquid Crystal Orientation in the Lipid Layer on Tear Film Thinning and Breakup

MJ Taranchuk, RJ Braun - arxiv preprint arxiv:2404.13225, 2024 - arxiv.org
The human tear film (TF) is thin multilayer fluid film that is critical for clear vision and ocular
surface health. Its dynamics are strongly affected by a floating lipid layer and, in health, that …

Dynamics of a gel-based artificial tear film with an emphasis on dry disease treatment applications

H Mehdaoui, H Ait Abderrahmane, C de Loubens… - Gels, 2021 - mdpi.com
This paper discusses the spreading of gel-based ophthalmic formulation on the cornea
surface assumed to be flat. We show that gel-based formulations exhibit rheological …

Fitting ODE models of tear film breakup

TA Driscoll, RJ Braun, RA Luke, D Sinopoli… - arxiv preprint arxiv …, 2022 - arxiv.org
The contribution of different physical effects to tear breakup (TBU) in subjects with no self-
reported history of dry eye are quantified. An automated system using a convolutional neural …

On modeling tear breakup dynamics with a nematic lipid layer

MJ Taranchuk, RJ Braun - Journal of Engineering Mathematics, 2024 - Springer
One of the main roles of the lipid layer (LL) of the tear film (TF) is to help prevent evaporation
of the aqueous layer (AL). The LL thickness, composition, and structure all contribute to its …

A Perspective on the Use of Fluorescent Imaging to Reveal Mechanisms of Breakup

PE King-Smith, C Begley, RJ Braun - Current Eye Research, 2022 - Taylor & Francis
Purpose: Tear film instability, which can lead to rapid tear film breakup (TBU), is considered
to be a major etiological factor in dry eye. However, experimental support for many of the …

Nematic Liquid Crystal Models for the Lipid Layer of the Human Tear Film

MJ Taranchuk - 2024 - search.proquest.com
The human tear film is a thin, multilayer fluid film that protects and nourishes the eye and is
critical for clear vision and ocular surface health. The tear film's dynamics are strongly …