Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

Recent progress in protein-based nanomedicine, inspired by the success of Abraxane®
albumin-paclitaxel nanoparticles, have resulted in novel therapeutics used for treatment of …

Targeted delivery of drugs to the brain is challenging due to the restricted permeability
across the blood brain barrier (BBB). Gliomas are devastating cancers and their positive …

In recent years, nanomedicines have emerged as a promising method for central nervous
system drug delivery, enabling the drugs to overcome the blood-brain barrier and …

Carboplatin (CRBP) is a chemotherapeutic agent based on platinum that has applications in
the effective management of ovarian, testis, cervical, neck, head, and small cell lung cancer …

Quite recently, milk exosomes have been recognized as efficient drug delivery systems
owing to their biocompatibility and easy availability for scale-up technologies. However …

Chemotherapy protocols for childhood cancers are still problematic due to the high toxicity
associated with chemotherapeutic agents and incorrect dosing regimens extrapolated from …

Purpose: Cancer stem cells (CSCs) are known to contribute to tumor relapses by virtue of
their chemoresistance. With the knowledge that nanoformulations can overcome drug …

The paradigm of pediatric drug development has been evolving in a “carrot-and-stick”-based
tactic to address population-specific issues. However, the off-label prescription of adult …

Surface-modified, targeted nanocarriers play important roles in chemotherapy. The addition
of the ligand changes the chemical composition of the polymer; the ability to hold and …