Photodynamic therapy (PDT), a therapeutic mode involving light triggering, has been
recognized as an attractive oncotherapy treatment. However, nonnegligible challenges …

Despite their past triumphs, platinum-based therapeutics remain limited by chemo-
resistance and severe side effects. As an alternative therapeutic modality which bypasses …

Strained ruthenium (Ru) complexes have been synthesized and characterized as novel
agents for photodynamic therapy (PDT). The complexes are inert until triggered by visible …

Incorporation of biquinoline ligands into Ru (II) polypyridyl complexes produces light-
activated systems that eject a ligand and photobind DNA after irradiation with visible and …

Platinum-based anticancer drugs are among the most widely used antineoplastics in clinical
settings. Their therapeutic applications and outcomes are, however, greatly hampered by …

The new tris-heteroleptic complex [Ru (bpy)(dppn)(CH3CN) 2] 2+(3, bpy= 2, 2′-bipyridine,
dppn= benzo [i] dipyrido [3, 2-a; 2′, 3′-c] phenazine) was synthesized and characterized …

This article presents a short review of photosubstitution reactions of Ru (II) imine complexes
and illustrates their use in the development of potential therapeutic agents. The review …

Photodynamic therapy (PDT) requires a photosensitizing agent, which can undergo visible
light activation, yielding reactive oxygen species and/or radical species. The key physical …

Cell death by visible light: Photodynamic therapy (PDT) is a relatively underemployed
method for treatment of diseases including cancer. Recent improvements in synthetic and …

The purpose of the present study was to investigate the influence of π-expansive
cyclometalating ligands on the photophysical and photobiological properties of …