The emergence of carbapenem-resistant Gram-negative pathogens poses a serious threat
to public health worldwide. In particular, the increasing prevalence of carbapenem-resistant …

The gut microbiota has diverse and essential roles in host metabolism, development of the
immune system and as resistance to pathogen colonization. Perturbations of the gut …

Antimicrobial resistance poses a substantial threat to human health. The gut microbiome is
considered a reservoir for potential spread of resistance genes from commensals to …

Highlights•The human gut microbiome harbours antibiotic resistance genes ('the
resistome').•Antibiotic resistance genes can spread in the gut microbiome through horizontal …

Surveillance studies have shown that OXA-48-like carbapenemases are the most common
carbapenemases in Enterobacterales in certain regions of the world and are being …

The spread of antimicrobial resistance has become a serious public health concern, making
once-treatable diseases deadly again and undermining the achievements of modern …

ABSTRACT A global rise in antimicrobial resistance among pathogenic bacteria has proved
to be a major public health threat, with the rate of multidrug-resistant bacterial infections …

Infections caused by carbapenemase-producing enterobacteria (CPE) are a major concern
in clinical settings worldwide. Two fundamentally different processes shape the …

Infections caused by antibiotic‐resistant bacteria are a major public health threat. The
emergence and spread of antibiotic resistance genes (ARGs) in the environment or clinical …

The overuse, misuse, and underuse of antibiotics tend to increase the antibiotic burden in
the environment resulting into the evolution in microbial community to possess resistance …