Radiation track, DNA damage and response—a review

H Nikjoo, D Emfietzoglou, T Liamsuwan… - Reports on Progress …, 2016 - iopscience.iop.org
The purpose of this paper has been to review the current status and progress of the field of
radiation biophysics, and draw attention to the fact that physics, in general, and radiation …

Review of theories on ionization in fast ion-atom collisions with prospects for applications to hadron therapy

D Belkić - Journal of mathematical chemistry, 2010 - Springer
This study emphasizes the need for a systematic and in-depth connection between the
progress in quantum theory of energetic ion collisions and applications to hadron therapy …

Track-structure codes in radiation research

H Nikjoo, S Uehara, D Emfietzoglou… - Radiation …, 2006 - Elsevier
Monte Carlo track-structure simulation provides a near accurate description of the passage
of charge particle in water as a surrogate for biological tissue. Radiation transport codes and …

Benchmarking nuclear models of FLUKA and GEANT4 for carbon ion therapy

TT Böhlen, F Cerutti, M Dosanjh, A Ferrari… - Physics in Medicine …, 2010 - iopscience.iop.org
As carbon ions, at therapeutic energies, penetrate tissue, they undergo inelastic nuclear
reactions and give rise to significant yields of secondary fragment fluences. Therefore, an …

Experimental validation of the TOPAS Monte Carlo system for passive scattering proton therapy

M Testa, J Schümann, HM Lu, J Shin… - Medical …, 2013 - Wiley Online Library
Purpose: TOPAS (TOol for PArticle Simulation) is a particle simulation code recently
developed with the specific aim of making Monte Carlo simulations user‐friendly for …

Interaction vertex imaging (IVI) for carbon ion therapy monitoring: a feasibility study

P Henriquet, E Testa, M Chevallier… - Physics in Medicine …, 2012 - iopscience.iop.org
Proton imaging can be seen as a powerful technique for online monitoring of ion range
during carbon ion therapy irradiations. Indeed, a large number of secondary protons are …

Depth absorbed dose and LET distributions of therapeutic, and beams

J Kempe, I Gudowska, A Brahme - Medical physics, 2007 - Wiley Online Library
The depth absorbed dose and LET (linear energy transfer) distribution of different ions of
clinical interest such as,,, and ions have been investigated using the Monte Carlo code …

The FLUKA Monte Carlo code coupled with the local effect model for biological calculations in carbon ion therapy

A Mairani, S Brons, F Cerutti, A Fassò… - Physics in Medicine …, 2010 - iopscience.iop.org
Abstract Clinical Monte Carlo (MC) calculations for carbon ion therapy have to provide
absorbed and RBE-weighted dose. The latter is defined as the product of the dose and the …

Validation of recent Geant4 physics models for application in carbon ion therapy

A Lechner, VN Ivanchenko, J Knobloch - Nuclear Instruments and Methods …, 2010 - Elsevier
Cancer treatment with energetic carbon ions has distinct advantages over proton or photon
irradiation. In this paper we present a simulation model integrated into the Geant4 Monte …

Lineal energy and radiation quality in radiation therapy: model calculations and comparison with experiment

L Lindborg, M Hultqvist, ÅC Tedgren… - Physics in medicine & …, 2013 - iopscience.iop.org
Microdosimetry is a recommended method for characterizing radiation quality in situations
when the biological effectiveness under test is not well known. In such situations, the …