Liquid biopsy of cancer: a multimodal diagnostic tool in clinical oncology

R Palmirotta, D Lovero, P Cafforio… - … in medical oncology, 2018 - journals.sagepub.com
Over the last decades, the concept of precision medicine has dramatically renewed the field
of medical oncology; the introduction of patient-tailored therapies has significantly improved …

Circulating tumor DNA as biomarkers for cancer detection

X Han, J Wang, Y Sun - Genomics, Proteomics and …, 2017 - academic.oup.com
Detection of circulating tumor DNAs (ctDNAs) in cancer patients is an important component
of cancer precision medicine ctDNAs. Compared to the traditional physical and biochemical …

Identification of tissue-specific cell death using methylation patterns of circulating DNA

R Lehmann-Werman, D Neiman… - Proceedings of the …, 2016 - National Acad Sciences
Minimally invasive detection of cell death could prove an invaluable resource in many
physiologic and pathologic situations. Cell-free circulating DNA (cfDNA) released from dying …

Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer

L Barault, A Amatu, G Siravegna, A Ponzetti, S Moran… - Gut, 2018 - gut.bmj.com
Objective Mutations in cell-free circulating DNA (cfDNA) have been studied for tracking
disease relapse in colorectal cancer (CRC). This approach requires personalised assay …

Graphene-based field effect transistor biosensors for breast cancer detection: A review on biosensing strategies

I Novodchuk, M Bajcsy, M Yavuz - Carbon, 2021 - Elsevier
Breast cancer (BC) is the most occurring cancer in females and the second most commonly
occurring cancer world-wide. Early detection of BC may ease the treatment and prevent the …

Saliva based liquid biopsies in head and neck cancer: how far are we from the clinic?

A Patel, S Patel, P Patel, V Tanavde - Frontiers in oncology, 2022 - frontiersin.org
Head and neck cancer (HNC) remains to be a major cause of mortality worldwide because
of confounding factors such as late-stage tumor diagnosis, loco-regional aggressiveness …

[HTML][HTML] Circulating biomarkers in breast cancer

KN Seale, KHR Tkaczuk - Clinical breast cancer, 2022 - Elsevier
Breast cancer management has progressed immensely over the decades, but the disease is
still a major source of morbidity and mortality worldwide. Even with enhanced imaging …

Vorinostat (SAHA) and breast cancer: an overview

A Wawruszak, L Borkiewicz, E Okon, W Kukula-Koch… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer (BC) is the most frequent malignancy diagnosed in 2020
worldwide. Despite significant advances in BC therapy, its pathogenesis is still not fully …

Epigenetic biomarkers in cell-free DNA and applications in liquid biopsy

W Gai, K Sun - Genes, 2019 - mdpi.com
Cell-free circulating DNA (cfDNA) in plasma has gained global interest as a diagnostic
material for noninvasive prenatal testing and cancer diagnosis, or the so-called “liquid …

[HTML][HTML] Targeted methylation sequencing of plasma cell-free DNA for cancer detection and classification

L Liu, JM Toung, AF Jassowicz, R Vijayaraghavan… - Annals of …, 2018 - Elsevier
Background Targeted methylation sequencing of plasma cell-free DNA (cfDNA) has a
potential to expand liquid biopsies to patients with tumors without detectable oncogenic …