[HTML][HTML] Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies
Pseudomonas aeruginosa is an opportunistic pathogen that is a leading cause of morbidity
and mortality in cystic fibrosis patients and immunocompromised individuals. Eradication of …
and mortality in cystic fibrosis patients and immunocompromised individuals. Eradication of …
Strategies for combating bacterial biofilms: A focus on anti-biofilm agents and their mechanisms of action
Biofilm refers to the complex, sessile communities of microbes found either attached to a
surface or buried firmly in an extracellular matrix as aggregates. The biofilm matrix …
surface or buried firmly in an extracellular matrix as aggregates. The biofilm matrix …
Biofilms as promoters of bacterial antibiotic resistance and tolerance
C Uruén, G Chopo-Escuin, J Tommassen… - Antibiotics, 2020 - mdpi.com
Multidrug resistant bacteria are a global threat for human and animal health. However, they
are only part of the problem of antibiotic failure. Another bacterial strategy that contributes to …
are only part of the problem of antibiotic failure. Another bacterial strategy that contributes to …
Bacterial biofilms: from the natural environment to infectious diseases
L Hall-Stoodley, JW Costerton… - Nature reviews …, 2004 - nature.com
Biofilms—matrix-enclosed microbial accretions that adhere to biological or non-biological
surfaces—represent a significant and incompletely understood mode of growth for bacteria …
surfaces—represent a significant and incompletely understood mode of growth for bacteria …
Bacterial quorum sensing: its role in virulence and possibilities for its control
ST Rutherford, BL Bassler - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
Quorum sensing is a process of cell–cell communication that allows bacteria to share
information about cell density and adjust gene expression accordingly. This process …
information about cell density and adjust gene expression accordingly. This process …
The role of root exudates in rhizosphere interactions with plants and other organisms
The rhizosphere encompasses the millimeters of soil surrounding a plant root where
complex biological and ecological processes occur. This review describes recent advances …
complex biological and ecological processes occur. This review describes recent advances …
The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation
The widespread use of antibiotics in the past 80 years has saved millions of human lives,
facilitated technological progress and killed incalculable numbers of microbes, both …
facilitated technological progress and killed incalculable numbers of microbes, both …
Biofilm-related infections: bridging the gap between clinical management and fundamental aspects of recalcitrance toward antibiotics
Surface-associated microbial communities, called biofilms, are present in all environments.
Although biofilms play an important positive role in a variety of ecosystems, they also have …
Although biofilms play an important positive role in a variety of ecosystems, they also have …
The role of bacterial biofilms in chronic infections
T Bjarnsholt - Apmis, 2013 - Wiley Online Library
Acute infections caused by pathogenic bacteria have been studied extensively for well over
100 years. These infections killed millions of people in previous centuries, but they have …
100 years. These infections killed millions of people in previous centuries, but they have …
Quorum sensing inhibitors: an overview
VC Kalia - Biotechnology advances, 2013 - Elsevier
Excessive and indiscriminate use of antibiotics to treat bacterial infections has lead to the
emergence of multiple drug resistant strains. Most infectious diseases are caused by …
emergence of multiple drug resistant strains. Most infectious diseases are caused by …