In cancer medicine, next generation sequencing (NGS) has emerged as a practical method
to generate patient-and tumor-specific genetic data for optimal selection of targeted …

Modern genomic approaches have made enormous contributions to improving our
understanding of the function, development and evolution of the nervous system, and the …

The co-authors of this paper hereby state their intention to work together to launch the
Genomic Observatories Network (GOs Network) for which this document will serve as its …

Context.—Most current proficiency testing challenges for next-generation sequencing
assays are methods-based proficiency testing surveys that use DNA from characterized …

Purpose Next-generation sequencing technologies are actively applied in clinical oncology.
Bioinformatics pipeline analysis is an integral part of this process; however, humans cannot …

Background Next-generation sequencing (NGS) is a useful tool for evaluating patients with
suspected genetic kidney disease. Clinical practice relies on the use of targeted gene …

We have developed an informatics system, GeneMed, for the National Cancer Institute (NCI)
molecular profiling-based assignment of cancer therapy (MPACT) clinical trial …

Laboratory information systems (LISs) have some basic functionality necessary for
molecular workflow that is glaringly absent. This study determined functionality gaps of LISs …

Next‐generation sequencing (NGS) has become an important tool for identifying clinically
relevant variants in both inherited disorders and oncology. Variants annotation that enables …

Next-generation sequencing (NGS) diagnostic assays increasingly are becoming the
standard of care in oncology practice. As the scale of an NGS laboratory grows …