Highlights•Multiple levels of metabolic engineering can be defined, from 'copy and paste'to
various forms of 'synthetic metabolism'.•The biochemical solution space for 'synthetic …

Strictly anaerobic, acetogenic (acetate-forming) bacteria are characterized by a reductive
pathway in which two mol of CO 2 are reduced to one mol of acetyl coenzyme A (acetyl …

Six CO 2 fixation pathways are known to operate in photoautotrophic and chemoautotrophic
microorganisms. Here, we describe chemolithoautotrophic growth of the sulphate-reducing …

Formate may become an ideal mediator between the physicochemical and biological
realms, as it can be produced efficiently from multiple available sources, such as electricity …

Acetogenic bacteria are already established as biocatalysts for production of high‐value
compounds from C1 substrates such as H2+ CO2 or CO. However, little is known about the …

Formate has great potential to function as a feedstock for biorefineries because it can be
sustainably produced by a variety of processes that don't compete with agricultural …

Highlights•Inorganic carbon can enter cellular metabolism via carboxylation or
reduction.•CO 2 reducing enzymes can be as proficient as carboxylating …

Metabolism has long been considered as a relatively stiff set of biochemical reactions. This
somewhat outdated and dogmatic view has been challenged over the last years, as multiple …

Enzymatic carbon dioxide fixation is one of the most important metabolic reactions as it
allows the capture of inorganic carbon from the atmosphere and its conversion into organic …

With the goal of achieving carbon sequestration, emission reduction and cleaner production,
biological methods have been employed to convert carbon dioxide (CO2) into fuels and …