Objectives Efforts towards achieving durable resin–dentin bonds have been made for
decades, including the understanding of the mechanisms underlying hybrid layer (HL) …

Objective Success in adhesive dentistry means long lasting restorations. However, there is
substantial evidence that this ideal objective is not always achieved. Current research in this …

Dentin can be described as a biological composite with collagen matrix embedded with
nanosized hydroxyapatite mineral crystallites. Matrix metalloproteinases (MMPs) and …

Unlike other fluoride-based caries preventive agents, silver diamine fluoride (SDF) can
simultaneously prevent and arrest coronal and root dentine caries. The profound clinical …

Objectives: The aim of this study was to explore the therapeutic opportunities of each step of
3-step etch-and-rinse adhesives. Methods: Etch-and-rinse adhesive systems are the oldest …

Objective Endogenous dentin collagenolytic enzymes, matrix metalloproteinases (MMPs)
and cysteine cathepsins, are responsible for the time-dependent hydrolysis of collagen …

The limited durability of resin-dentin bonds severely compromises the lifetime of tooth-
colored restorations. Bond degradation occurs via hydrolysis of suboptimally polymerized …

OBJECTIVES: Contemporary adhesives lose their bond strength to dentin regardless of the
bonding system used. This loss relates to the hydrolysis of collagen matrix of the hybrid …

Objectives Remineralization of demineralized dentin is important for improving dentin
bonding stability and controlling primary and secondary caries. Nevertheless, conventional …

In dentin bonding, contemporary dental adhesive systems rely on formation of the hybrid
layer, a biocomposite containing dentin collagen and polymerized resin adhesive. They are …