Thiazole ring—A biologically active scaffold

A Petrou, M Fesatidou, A Geronikaki - Molecules, 2021 - mdpi.com
Background: Thiazole is a good pharmacophore nucleus due to its various pharmaceutical
applications. Its derivatives have a wide range of biological activities such as antioxidant …

Enantioselective activity of usnic acid: A comprehensive review and future perspectives

A Galanty, P Paśko, I Podolak - Phytochemistry Reviews, 2019 - Springer
This review is focused on the comparison of the biological and pharmacological activities of
usnic acid enantiomers. Most of the available data refer to (+)-usnic acid, while the left …

What are the prospects for using complexes of copper (II) and zinc (II) to suppress the vital activity of Mycolicibacterium smegmatis?

IA Lutsenko, DE Baravikov, KA Koshenskova… - RSC …, 2022 - pubs.rsc.org
New complexes of zinc (II) and copper (II) with 2-furoic acid (Hfur), acetic acids and N-donor
ligands with the compositions [Zn2 (fur) 4] n (1),[Zn2 (fur) 4 (NH2py) 2](2, NH2py= 3 …

Novel tyrosyl-DNA phosphodiesterase 1 inhibitors enhance the therapeutic impact of topoteсan on in vivo tumor models

AL Zakharenko, OA Luzina, DN Sokolov… - European Journal of …, 2019 - Elsevier
The druggability of the tyrosyl-DNA phosphodiesterase 1 (Tdp1) enzyme was investigated in
conjunction with topoisomerase 1 inhibition. A novel class of thiazole, aminothiazole and …

Copper (II) complexes with 5-nitro-2-furoic acid: synthesis, structure, thermal properties, and biological activity

KA Koshenskova, IA Lutsenko, YV Nelyubina… - Russian Journal of …, 2022 - Springer
Reaction of copper (II) acetate with 5-nitro-2-furoic acid (NO2-Hfur) and N-donor ligands 2, 2'‑
bipyridine (bpy) and pyridine (py) has resulted in complexes [Cu (NO2-fur) 2 (H2O) 2]· 2H2O …

Effects of carnosic and usnic acid on pentose phosphate pathway enzymes: an experimental and molecular docking study

Y Demir, N Öztürk, M Isıyel, H Ceylan - ChemistrySelect, 2024 - Wiley Online Library
phosphogluconate dehydrogenase (6PGD) and Glucose‐6‐phosphate dehydrogenase
(G6PD) are crucial enzymes involved in generating cellular reducing power. Modifying the …

Nickel (II) complexes with 2-Hfur and N-donors: The magnetic effects of the structural variations, thermal properties and antimycobacterial activity against …

MA Uvarova, IA Lutsenko, MA Kiskin, YV Nelyubina… - Polyhedron, 2021 - Elsevier
New complexes of nickel (II) with 2-furoic acid (2-Hfur) and different N-donor ligands of the
composition [Ni (fur) 2 (phen)(H 2 O) 2]· H 2 O (1)(phen= 1, 10-phenantroline),[Ni (fur) 2 (2 …

Improved In Vitro Antimycobacterial Activity of Trinuclear Complexes Cobalt(II,III) and Iron(III) with 2‐Furoic Acid against Mycolicibacterium smegmatis

IA Lutsenko, DS Yambulatov, MA Kiskin… - …, 2020 - Wiley Online Library
The reaction of cobalt (II) and iron (III) pivalates with anions of 2‐furancarboxylic acid
(pyromucic acid, Hfur) yielded trinuclear homometallic complexes with linear ([Co3 (fur) 6 …

Mononuclear Cu (II), Zn (II), and Co (II) Complexes with 2-Furoate Anions and 2, 2'-Bpy: Synthesis, Structure, and Biological Activity

IA Lutsenko, DS Yambulatov, MA Kiskin… - Russian Journal of …, 2020 - Springer
The mononuclear complexes [M (Fur) 2 (Bpy)(H 2 O)](M= Cu (I), Zn (II)) were prepared by
the reactions of copper (II) and zinc (II) acetates with 2-furoic acid (HFur) anion and 2, 2' …

Synthesis, structure, and in vitro evaluation of biological activity of CuII furancarboxylates against the non-pathogenic M. smegmatis strain

IA Lutsenko, MA Kiskin, KA Koshenskova… - Russian Chemical …, 2021 - Springer
The reaction of copper (ii) acetate with 2-furancarboxylate (Hfur, pyromucate) anions and the
N-donor ligands 4-phenylpyridine (phpy) and 3-aminopyridine (NH 2 py) in acetonitrile …