Merkel cell carcinoma

JC Becker, A Stang, JA DeCaprio, L Cerroni… - Nature reviews Disease …, 2017‏ - nature.com
Merkel cell carcinoma (MCC) is a rare but highly aggressive skin cancer with
neuroendocrine features. MCC pathogenesis is associated with either the presence of …

Molecular pathogenesis of Merkel cell carcinoma

JA DeCaprio - Annual Review of Pathology: Mechanisms of …, 2021‏ - annualreviews.org
Merkel cell carcinoma (MCC) is an aggressive neuroendocrine carcinoma of the skin with
two distinct etiologies. Clonal integration of Merkel cell polyomavirus DNA into the tumor …

[HTML][HTML] Merkel cell polyomavirus and Merkel cell carcinoma

V Pietropaolo, C Prezioso, U Moens - Cancers, 2020‏ - mdpi.com
Viruses are the cause of approximately 15% of all human cancers. Both RNA and DNA
human tumor viruses have been identified, with Merkel cell polyomavirus being the most …

Human polyomaviruses and cancer: an overview

JCM Prado, TA Monezi, AT Amorim, V Lino, A Paladino… - Clinics, 2018‏ - SciELO Brasil
The name of the family Polyomaviridae, derives from the early observation that cells infected
with murine polyomavirus induced multiple (poly) tumors (omas) in immunocompromised …

Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis

J Cheng, DE Park, C Berrios, EA White, R Arora… - PLoS …, 2017‏ - journals.plos.org
Merkel cell carcinoma (MCC) frequently contains integrated copies of Merkel cell
polyomavirus DNA that express a truncated form of Large T antigen (LT) and an intact Small …

Therapeutic approaches for Non-melanoma skin Cancer: Standard of Care and Emerging modalities

S Sol, F Boncimino, K Todorova, SE Waszyn… - International Journal of …, 2024‏ - mdpi.com
Skin cancer encompasses a range of cutaneous malignancies, with non-melanoma skin
cancers (NMSCs) being the most common neoplasm worldwide. Skin exposure is the …

Epidemiology, biology and therapy of Merkel cell carcinoma: conclusions from the EU project IMMOMEC

JC Becker, A Stang, A Hausen, N Fischer… - Cancer Immunology …, 2018‏ - Springer
Merkel cell carcinoma (MCC) is a highly aggressive, often lethal neuroendocrine cancer. Its
carcinogenesis may be either caused by the clonal integration of the Merkel cell …

Epigenetic dysregulations in merkel cell polyomavirus-driven merkel cell carcinoma

JC Rotondo, C Mazziotta, C Lanzillotti… - International Journal of …, 2021‏ - mdpi.com
Merkel cell polyomavirus (MCPyV) is a small DNA virus with oncogenic potential. MCPyV is
the causative agent of Merkel Cell Carcinoma (MCC), a rare but aggressive tumor of the …

Merkel cell polyomavirus and Merkel cell carcinoma

JA DeCaprio - … Transactions of the Royal Society B …, 2017‏ - royalsocietypublishing.org
Merkel cell polyomavirus (MCPyV) causes the highly aggressive and relatively rare skin
cancer known as Merkel cell carcinoma (MCC). MCPyV also causes a lifelong yet relatively …

The role of histone post-translational modifications in merkel cell carcinoma

C Mazziotta, C Lanzillotti, R Gafà, A Touzé… - Frontiers in …, 2022‏ - frontiersin.org
Merkel Cell Carcinoma (MCC) is a rare but highly aggressive form of non–melanoma skin
cancer whose 5-year survival rate is 63%. Merkel cell polyomavirus (MCPyV), a small DNA …