[HTML][HTML] Circadian rhythm disruption and mental health
Circadian rhythms are internal manifestations of the solar day that permit adaptations to
predictable environmental temporal changes. These~ 24-h rhythms are controlled by …
predictable environmental temporal changes. These~ 24-h rhythms are controlled by …
The schizophrenia syndrome, circa 2024: What we know and how that informs its nature
R Tandon, H Nasrallah, S Akbarian… - Schizophrenia …, 2024 - Elsevier
With new data about different aspects of schizophrenia being continually generated, it
becomes necessary to periodically revisit exactly what we know. Along with a need to review …
becomes necessary to periodically revisit exactly what we know. Along with a need to review …
Multi-trait analysis for genome-wide association study of five psychiatric disorders
We conducted a cross-trait meta-analysis of genome-wide association study on
schizophrenia (SCZ)(n= 65,967), bipolar disorder (BD)(n= 41,653), autism spectrum …
schizophrenia (SCZ)(n= 65,967), bipolar disorder (BD)(n= 41,653), autism spectrum …
Heritability of schizophrenia and schizophrenia spectrum based on the nationwide Danish twin register
R Hilker, D Helenius, B Fagerlund, A Skytthe… - Biological …, 2018 - Elsevier
Background Twin studies have provided evidence that both genetic and environmental
factors contribute to schizophrenia (SZ) risk. Heritability estimates of SZ in twin samples …
factors contribute to schizophrenia (SZ) risk. Heritability estimates of SZ in twin samples …
Sexual orientation, controversy, and science
Ongoing political controversies around the world exemplify a long-standing and widespread
preoccupation with the acceptability of homosexuality. Nonheterosexual people have seen …
preoccupation with the acceptability of homosexuality. Nonheterosexual people have seen …
The inflamed brain in schizophrenia: the convergence of genetic and environmental risk factors that lead to uncontrolled neuroinflammation
Schizophrenia is a disorder with a heterogeneous etiology involving complex interplay
between genetic and environmental risk factors. The immune system is now known to play …
between genetic and environmental risk factors. The immune system is now known to play …
Maternal immune activation and abnormal brain development across CNS disorders
I Knuesel, L Chicha, M Britschgi, SA Schobel… - Nature Reviews …, 2014 - nature.com
Epidemiological studies have shown a clear association between maternal infection and
schizophrenia or autism in the progeny. Animal models have revealed maternal immune …
schizophrenia or autism in the progeny. Animal models have revealed maternal immune …
Biological hypotheses, risk factors, and biomarkers of schizophrenia
Z Fišar - Progress in Neuro-Psychopharmacology and …, 2023 - Elsevier
Both the discovery of biomarkers of schizophrenia and the verification of biological
hypotheses of schizophrenia are an essential part of the process of understanding the …
hypotheses of schizophrenia are an essential part of the process of understanding the …
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
… Consortium Manuscript preparation Purcell Shaun M … - Nature, 2009 - nature.com
Schizophrenia is a severe mental disorder with a lifetime risk of about 1%, characterized by
hallucinations, delusions and cognitive deficits, with heritability estimated at up to 80%,. We …
hallucinations, delusions and cognitive deficits, with heritability estimated at up to 80%,. We …
Schizophrenia: a tale of two critical periods for prefrontal cortical development
Schizophrenia is a disease of abnormal brain development. Considerable evidence now
indicates that environmental factors have a causative role in schizophrenia. Elevated …
indicates that environmental factors have a causative role in schizophrenia. Elevated …