Interaction between microbiota and immunity in health and disease
The interplay between the commensal microbiota and the mammalian immune system
development and function includes multifold interactions in homeostasis and disease. The …
development and function includes multifold interactions in homeostasis and disease. The …
T follicular helper cell biology: a decade of discovery and diseases
S Crotty - Immunity, 2019 - cell.com
Hel** B cells and antibody responses is a major function of CD4+ T cells. It has been 10
years since the publication of Bcl6 as the lineage-defining transcription factor for T follicular …
years since the publication of Bcl6 as the lineage-defining transcription factor for T follicular …
Gut biogeography of the bacterial microbiota
Animals assemble and maintain a diverse but host-specific gut microbial community. In
addition to characteristic microbial compositions along the longitudinal axis of the intestines …
addition to characteristic microbial compositions along the longitudinal axis of the intestines …
The microbiota in adaptive immune homeostasis and disease
K Honda, DR Littman - Nature, 2016 - nature.com
In the mucosa, the immune system's T cells and B cells have position-specific phenotypes
and functions that are influenced by the microbiota. These cells play pivotal parts in the …
and functions that are influenced by the microbiota. These cells play pivotal parts in the …
Host–microbiota interactions in inflammatory bowel disease
The mammalian intestine is colonized by trillions of microorganisms that have co-evolved
with the host in a symbiotic relationship. The presence of large numbers of symbionts near …
with the host in a symbiotic relationship. The presence of large numbers of symbionts near …
[HTML][HTML] The interplay between the gut microbiome and the immune system in the context of infectious diseases throughout life and the role of nutrition in optimizing …
Infectious diseases and infections remain a leading cause of death in low-income countries
and a major risk to vulnerable groups, such as infants and the elderly. The immune system …
and a major risk to vulnerable groups, such as infants and the elderly. The immune system …
[HTML][HTML] Ketogenic diets alter the gut microbiome resulting in decreased intestinal Th17 cells
Very low-carbohydrate, high-fat ketogenic diets (KDs) induce a pronounced shift in
metabolic fuel utilization that elevates circulating ketone bodies; however, the …
metabolic fuel utilization that elevates circulating ketone bodies; however, the …
Gut microbiota utilize immunoglobulin A for mucosal colonization
The immune system responds vigorously to microbial infection while permitting lifelong
colonization by the microbiome. Mechanisms that facilitate the establishment and stability of …
colonization by the microbiome. Mechanisms that facilitate the establishment and stability of …
Expansion of bacteriophages is linked to aggravated intestinal inflammation and colitis
Bacteriophages are the most abundant members of the microbiota and have the potential to
shape gut bacterial communities. Changes to bacteriophage composition are associated …
shape gut bacterial communities. Changes to bacteriophage composition are associated …
Acetate differentially regulates IgA reactivity to commensal bacteria
T Takeuchi, E Miyauchi, T Kanaya, T Kato, Y Nakanishi… - Nature, 2021 - nature.com
The balance between bacterial colonization and its containment in the intestine is
indispensable for the symbiotic relationship between humans and their bacteria. One …
indispensable for the symbiotic relationship between humans and their bacteria. One …