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Mining genomes to illuminate the specialized chemistry of life
All organisms produce specialized organic molecules, ranging from small volatile chemicals
to large gene-encoded peptides, that have evolved to provide them with diverse cellular and …
to large gene-encoded peptides, that have evolved to provide them with diverse cellular and …
Mind the mushroom: natural product biosynthetic genes and enzymes of Basidiomycota
Covering: up to September 2020 Mushroom-forming fungi of the division Basidiomycota
have traditionally been recognised as prolific producers of structurally diverse and often …
have traditionally been recognised as prolific producers of structurally diverse and often …
Disarming the host: detoxification of plant defense compounds during fungal necrotrophy
While fungal biotrophs are dependent on successfully suppressing/subverting host defenses
during their interaction with live cells, necrotrophs, due to their lifestyle are often confronted …
during their interaction with live cells, necrotrophs, due to their lifestyle are often confronted …
[PDF][PDF] The architecture of metabolism maximizes biosynthetic diversity in the largest class of fungi
Ecological diversity in fungi is largely defined by metabolic traits, including the ability to
produce secondary or “specialized” metabolites (SMs) that mediate interactions with other …
produce secondary or “specialized” metabolites (SMs) that mediate interactions with other …
Dynamics in Secondary Metabolite Gene Clusters in Otherwise Highly Syntenic and Stable Genomes in the Fungal Genus Botrytis
Fungi of the genus Botrytis infect> 1,400 plant species and cause losses in many crops.
Besides the broad host range pathogen Botrytis cinerea, most other species are restricted to …
Besides the broad host range pathogen Botrytis cinerea, most other species are restricted to …
CLOCI: unveiling cryptic fungal gene clusters with generalized detection
Gene clusters are genomic loci that contain multiple genes that are functionally and
genetically linked. Gene clusters collectively encode diverse functions, including small …
genetically linked. Gene clusters collectively encode diverse functions, including small …
Endophyte genomes support greater metabolic gene cluster diversity compared with non-endophytes in Trichoderma
Trichoderma is a cosmopolitan genus with diverse lifestyles and nutritional modes, including
mycotrophy, saprophytism, and endophytism. Previous research has reported greater …
mycotrophy, saprophytism, and endophytism. Previous research has reported greater …
Metabolic gene clusters, fungal diversity, and the generation of accessory functions
Highlights•Many of life's adaptive accessory functions are encoded in metabolic gene
clusters.•Cluster evolution is intertwined with the processes generating accessory …
clusters.•Cluster evolution is intertwined with the processes generating accessory …
Ecological generalism drives hyperdiversity of secondary metabolite gene clusters in xylarialean endophytes
Although secondary metabolites are typically associated with competitive or pathogenic
interactions, the high bioactivity of endophytic fungi in the Xylariales, coupled with their …
interactions, the high bioactivity of endophytic fungi in the Xylariales, coupled with their …
Rapid Divergence of Genome Architectures Following the Origin of an Ectomycorrhizal Symbiosis in the Genus Amanita
Fungi are evolutionary shape shifters and adapt quickly to new environments.
Ectomycorrhizal (EM) symbioses are mutualistic associations between fungi and plants and …
Ectomycorrhizal (EM) symbioses are mutualistic associations between fungi and plants and …