Cystic fibrosis (CF) is one of the most common life-shortening genetic diseases in
Caucasians. Due to abnormal accumulation of mucus, respiratory failure caused by chronic …

Objectives Cystic fibrosis (CF) lung disease is characterised by mucus stasis, chronic
infection and inflammation, causing progressive structural lung disease and eventual …

Rationale: Recent data show that Aspergillus species are prevalent respiratory infections in
children with cystic fibrosis (CF). The biological significance of these infections is unknown …

Rationale: Historical studies suggest that airway infection in cystic fibrosis initiates with
Staphylococcus aureus and Haemophilus influenzae, with later emergence of …

Pseudomonas aeruginosa is one of the most prominent opportunistic bacteria in airways of
cystic fibrosis patients and in immunocompromised patients. These bacteria share the same …

Background The clinical effects of Aspergillus fumigatus in the cystic fibrosis (CF) airway,
with the exception of allergic bronchopulmonary aspergillosis, is unclear. Methods CF …

Progress and challenges in fungal lung disease in cystic fib... : Current Opinion in
Pulmonary Medicine Progress and challenges in fungal lung disease in cystic fibrosis …

Rationale The clinical significance of Aspergillus fumigatus (Af) detection in the absence of
allergic bronchopulmonary aspergillosis in cystic fibrosis (CF) airways remains unclear. Yet …

Rationale: The pathogenicity of Aspergillus in the cystic fibrosis (CF) airway is debated,
leading to unclear clinical benefit of antifungal therapy for Aspergillus infection. Objective: To …

Observational studies indicate that Aspergillus colonization and allergic bronchopulmonary
aspergillosis (ABPA) in people with cystic fibrosis (CF) are associated with poorer lung …