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Slow-wave sleep: from the cell to the clinic
In recent decades, increasing evidence has positioned slow-wave sleep (SWS) as a major
actor in neurophysiological phenomena such as glucose metabolism, hormone release …
actor in neurophysiological phenomena such as glucose metabolism, hormone release …
Exploring phylogeny to find the function of sleep
During sleep, animals do not eat, reproduce or forage. Slee** animals are vulnerable to
predation. Yet, the persistence of sleep despite evolutionary pressures, and the deleterious …
predation. Yet, the persistence of sleep despite evolutionary pressures, and the deleterious …
Wake-like skin patterning and neural activity during octopus sleep
While slee**, many vertebrate groups alternate between at least two sleep stages: rapid
eye movement and slow wave sleep,,–, in part characterized by wake-like and synchronous …
eye movement and slow wave sleep,,–, in part characterized by wake-like and synchronous …
Sleep: a health imperative
Chronic sleep deficiency, defined as a state of inadequate or mistimed sleep, is a growing
and underappreciated determinant of health status. Sleep deprivation contributes to a …
and underappreciated determinant of health status. Sleep deprivation contributes to a …
[HTML][HTML] Functions and mechanisms of sleep
Sleep is a complex physiological process that is regulated globally, regionally, and locally
by both cellular and molecular mechanisms. It occurs to some extent in all animals, although …
by both cellular and molecular mechanisms. It occurs to some extent in all animals, although …
Reduced neural feedback signaling despite robust neuron and gamma auditory responses during human sleep
During sleep, sensory stimuli rarely trigger a behavioral response or conscious perception.
However, it remains unclear whether sleep inhibits specific aspects of sensory processing …
However, it remains unclear whether sleep inhibits specific aspects of sensory processing …
[HTML][HTML] The energy allocation function of sleep: a unifying theory of sleep, torpor, and continuous wakefulness
MH Schmidt - Neuroscience & Biobehavioral Reviews, 2014 - Elsevier
The energy allocation (EA) model defines behavioral strategies that optimize the temporal
utilization of energy to maximize reproductive success. This model proposes that all species …
utilization of energy to maximize reproductive success. This model proposes that all species …
Is sleep essential?
No current hypothesis can explain why animals need to sleep. Yet, sleep is universal, tightly
regulated, and cannot be deprived without deleterious consequences. This suggests that …
regulated, and cannot be deprived without deleterious consequences. This suggests that …
Sleep viewed as a state of adaptive inactivity
JM Siegel - Nature Reviews Neuroscience, 2009 - nature.com
Sleep is often viewed as a vulnerable state that is incompatible with behaviours that nourish
and propagate species. This has led to the hypothesis that sleep has survived because it …
and propagate species. This has led to the hypothesis that sleep has survived because it …
[HTML][HTML] Slow-wave sleep is controlled by a subset of nucleus accumbens core neurons in mice
Y Oishi, Q Xu, L Wang, BJ Zhang, K Takahashi… - Nature …, 2017 - nature.com
Sleep control is ascribed to a two-process model, a widely accepted concept that posits
homoeostatic drive and a circadian process as the major sleep-regulating factors. Cognitive …
homoeostatic drive and a circadian process as the major sleep-regulating factors. Cognitive …