Slow-wave sleep: from the cell to the clinic

D Léger, E Debellemaniere, A Rabat, V Bayon… - Sleep medicine …, 2018 - Elsevier
In recent decades, increasing evidence has positioned slow-wave sleep (SWS) as a major
actor in neurophysiological phenomena such as glucose metabolism, hormone release …

Exploring phylogeny to find the function of sleep

RC Anafi, MS Kayser, DM Raizen - Nature Reviews Neuroscience, 2019 - nature.com
During sleep, animals do not eat, reproduce or forage. Slee** animals are vulnerable to
predation. Yet, the persistence of sleep despite evolutionary pressures, and the deleterious …

Wake-like skin patterning and neural activity during octopus sleep

A Pophale, K Shimizu, T Mano, TL Iglesias, K Martin… - Nature, 2023 - nature.com
While slee**, many vertebrate groups alternate between at least two sleep stages: rapid
eye movement and slow wave sleep,,–, in part characterized by wake-like and synchronous …

Sleep: a health imperative

FS Luyster, PJ Strollo Jr, PC Zee, JK Walsh - Sleep, 2012 - academic.oup.com
Chronic sleep deficiency, defined as a state of inadequate or mistimed sleep, is a growing
and underappreciated determinant of health status. Sleep deprivation contributes to a …

[HTML][HTML] Functions and mechanisms of sleep

MR Zielinski, JT McKenna, RW McCarley - AIMS neuroscience, 2016 - ncbi.nlm.nih.gov
Sleep is a complex physiological process that is regulated globally, regionally, and locally
by both cellular and molecular mechanisms. It occurs to some extent in all animals, although …

Reduced neural feedback signaling despite robust neuron and gamma auditory responses during human sleep

H Hayat, A Marmelshtein, AJ Krom, Y Sela… - Nature …, 2022 - nature.com
During sleep, sensory stimuli rarely trigger a behavioral response or conscious perception.
However, it remains unclear whether sleep inhibits specific aspects of sensory processing …

[HTML][HTML] The energy allocation function of sleep: a unifying theory of sleep, torpor, and continuous wakefulness

MH Schmidt - Neuroscience & Biobehavioral Reviews, 2014 - Elsevier
The energy allocation (EA) model defines behavioral strategies that optimize the temporal
utilization of energy to maximize reproductive success. This model proposes that all species …

Is sleep essential?

C Cirelli, G Tononi - PLoS biology, 2008 - journals.plos.org
No current hypothesis can explain why animals need to sleep. Yet, sleep is universal, tightly
regulated, and cannot be deprived without deleterious consequences. This suggests that …

Sleep viewed as a state of adaptive inactivity

JM Siegel - Nature Reviews Neuroscience, 2009 - nature.com
Sleep is often viewed as a vulnerable state that is incompatible with behaviours that nourish
and propagate species. This has led to the hypothesis that sleep has survived because it …

[HTML][HTML] Slow-wave sleep is controlled by a subset of nucleus accumbens core neurons in mice

Y Oishi, Q Xu, L Wang, BJ Zhang, K Takahashi… - Nature …, 2017 - nature.com
Sleep control is ascribed to a two-process model, a widely accepted concept that posits
homoeostatic drive and a circadian process as the major sleep-regulating factors. Cognitive …