Distinguishing features of current COVID-19 vaccines: knowns and unknowns of antigen presentation and modes of action

FX Heinz, K Stiasny - npj Vaccines, 2021 - nature.com
COVID-19 vaccines were developed with an unprecedented pace since the beginning of the
pandemic. Several of them have reached market authorization and mass production …

Epidemiology, pathogenesis, clinical presentations, diagnosis and treatment of COVID-19: a review of current evidence

S Rahman, MTV Montero, K Rowe… - Expert review of …, 2021 - Taylor & Francis
Introduction The COVID-19 pandemic has created a public health crisis, infected millions of
people, and caused a significant number of deaths. SARS-CoV-2 transmits from person to …

[HTML][HTML] Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses

H Pan, R Peto, AMH Restrepo, MP Preziosi… - The Lancet, 2022 - Elsevier
Summary Background The Solidarity trial among COVID-19 inpatients has previously
reported interim mortality analyses for four repurposed antiviral drugs. Lopinavir …

[HTML][HTML] The SARS-CoV-2 mutations versus vaccine effectiveness: New opportunities to new challenges

JA Malik, S Ahmed, A Mir, M Shinde, O Bender… - Journal of infection and …, 2022 - Elsevier
Abstract Background The SARS-CoV-2 coronavirus epidemic is hastening the discovery of
the most efficient vaccines. The development of cost-effective vaccines seems to be the only …

SARS-CoV-2 variants and vaccines

PR Krause, TR Fleming, IM Longini… - … England Journal of …, 2021 - Mass Medical Soc
Viral variants of concern may emerge with dangerous resistance to the immunity generated
by the current vaccines to prevent coronavirus disease 2019 (Covid-19). Moreover, if some …

Individual determinants of COVID-19 vaccine hesitancy

P Gerretsen, J Kim, F Caravaggio, L Quilty, M Sanches… - PloS one, 2021 - journals.plos.org
Background Novel coronavirus disease 2019 (COVID-19) vaccine hesitancy is a barrier to
achieving herd immunity, and thus, a prominent public health concern. This study aimed to …

Strategy for COVID-19 vaccination in India: the country with the second highest population and number of cases

VM Kumar, SR Pandi-Perumal, I Trakht… - npj Vaccines, 2021 - nature.com
Free vaccination against COVID-19 commenced in India on January 16, 2021, and the
government is urging all of its citizens to be immunized, in what is expected to be the largest …

[HTML][HTML] Comparing COVID-19 vaccine allocation strategies in India: A mathematical modelling study

BH Foy, B Wahl, K Mehta, A Shet, GI Menon… - International Journal of …, 2021 - Elsevier
Background The development and widespread use of an effective SARS-CoV-2 vaccine
could prevent substantial morbidity and mortality associated with COVID-19 and mitigate the …

RNA-dependent RNA polymerase (RdRp) inhibitors: The current landscape and repurposing for the COVID-19 pandemic

L Tian, T Qiang, C Liang, X Ren, M Jia, J Zhang… - European journal of …, 2021 - Elsevier
The widespread nature of several viruses is greatly credited to their rapidly altering RNA
genomes that enable the infection to persist despite challenges presented by host cells …

COVID-19 vaccines: current understanding on immunogenicity, safety, and further considerations

Q He, Q Mao, J Zhang, L Bian, F Gao, J Wang… - Frontiers in …, 2021 - frontiersin.org
The world has entered the second wave of the COVID-19 pandemic, and its intensity is
significantly higher than that of the first wave of early 2020. Many countries or regions have …