Introduction Polypharmacy is commonly associated with adverse health outcomes. There
are currently no meta-analyses of the prevalence of polypharmacy or factors associated with …

Background The prevalence of multimorbidity (the presence of two or more long-term
conditions) is rising internationally. Multimorbidity affects patients by increasing their burden …

Purpose To assess the prevalence of urgent hospitalization due to adverse drug reactions
(ADRs) in patients aged≥ 65 years, to compare the in-hospital mortality rates between …

The correct management of patients with multimorbidity remains one of the main challenges
for healthcare systems worldwide. In this study, we analyze the existence of multimorbidity …

Greater life expectancy in Europe over the past few decades has been translated into an
increasing burden of chronic diseases that accumulate as the population ages, whereas …

Objectives The objective was to identify the systematic associations among chronic diseases
and drugs in the form of patterns and to describe and clinically interpret the constituted …

Background Late-life depression often coincides with chronic somatic diseases and,
consequently, with polypharmacy, which may complicate medical treatment. Objective To …

Background The implementation of individual clinical practice guidelines in patients with
multimorbidity often results in polypharmacy. Our aim was to analyse medication use …

Purpose The purpose of this study was to determine whether excessive polypharmacy is
associated with a higher survival rate in polypathological patients. Patients and methods An …

Introduction Polypharmacy and multimorbidity pose escalating challenges. Despite
numerous attempts, interventions have yet to show consistent improvements in health …