Epilepsy, a neurological disease characterized by recurrent seizures, is often associated
with a history of previous lesions in the nervous system. Impaired regulation of the activation …

Inflammatory bowel disease (IBD) is a chronic disorder associated with the inflammation in
the digestive tract. The exact cause of IBD is unknown; nevertheless, in IBD, the …

Recently, mesenchymal stem/stromal cells (MSCs) therapy has become an emerging
therapeutic modality for the treatment of inflammatory bowel disease (IBD), given their …

Objective Metformin is used to treat type 2 diabetes. We sought to determine whether
metformin reduces inflammation, by regulating p-signal transducer and activator of …

Networks of cytokines have been implicated in both forms of inflammatory bowel disease
(IBD): Crohn's disease (CD) and ulcerative colitis (UC). While CD has associated with T …

Interleukin-23 (IL-23) is a proinflammatory cytokine produced mainly by macrophages and
antigen-presenting cells (APCs) after antigenic stimulation. IL-23 plays a significant role as a …

Autoimmune diseases (such as rheumatoid arthritis, asthma, autoimmune bowel disease)
are a complex disease. Improper activation of the immune system or imbalance of immune …

Abstract Objective Interleukin-17 (IL-17)-producing T helper (Th) 17 cells are considered as
a new subset of cells critical to the development of inflammatory bowel disease (IBD). We …

Immune cells not only affect tissue homeostasis at the site of inflammation but also exert
systemic effects contributing to multiple chronic conditions. Recent evidence clearly supports …

AIM: To determine the therapeutic efficacy of resveratrol on ulcerative colitis (UC) and its
underlying mechanisms. METHODS: The mouse UC model was developed using 5 …