A substantial body of evidence indicates cationic, arginine-rich peptides (CARPs) are
effective therapeutic compounds for a range of neurodegenerative pathologies, with …

Even after the centenary celebration of insulin discovery, there prevail challenges
concerning insulin aggregation, not only after repeated administration but also during …

Compared to subcutaneous injections, oral administration of insulin would be a preferred
route of drug administration for diabetic patients. For oral delivery, both liposomes and …

Given the significance of protein aggregation in proteinopathies and the development of
therapeutic protein pharmaceuticals, revamped interest in assessing and modelling the …

In order to explore the structural changes and products of histamine degradation by
multicopper oxidase (MCO) in Lactiplantibacillus plantarum LPZN19, a 1500 bp MCO gene …

Conspectus Insulin has remained indispensable in the treatment of diabetes since it was first
discovered in 1921. Unlike small molecular drugs, insulin and other protein drugs are prone …

Amino acids have been widely used in protein formulations to increase the protein's stability.
In this study, amino acids have been introduced as soft-templates to control the nucleation of …

The effect of protein chaperones HspB6 and the monomeric form of the protein 14-3-3ζ (14-3-
3ζm) on a test system based on thermal aggregation of UV-irradiated glycogen …

Silver nanoparticles (SNPs) synthesized extracellularly using extracts of the different genus
Pleurotus fungi samples, were tested for their potential to serve as the therapeutic agents …

Formation and accumulation of protein aggregates adversely affect intracellular processes
in living cells and are negative factors in the production and storage of protein preparations …