Modelling human brain development and disease with organoids
Organoids are systems derived from pluripotent stem cells at the interface between
traditional monolayer cultures and in vivo animal models. The structural and functional …
traditional monolayer cultures and in vivo animal models. The structural and functional …
The use of single-cell RNA-seq to study heterogeneity at varying levels of virus–host interactions
The outcome of viral infection depends on the diversity of the infecting viral population and
the heterogeneity of the cell population that is infected. Until almost a decade ago, the study …
the heterogeneity of the cell population that is infected. Until almost a decade ago, the study …
Massively parallel characterization of regulatory elements in the develo** human cortex
Nucleotide changes in gene regulatory elements are important determinants of neuronal
development and diseases. Using massively parallel reporter assays in primary human cells …
development and diseases. Using massively parallel reporter assays in primary human cells …
Viral infections in etiology of mental disorders: a broad analysis of cytokine profile similarities–a narrative review
P Lorkiewicz, N Waszkiewicz - Frontiers in cellular and infection …, 2024 - frontiersin.org
The recent pandemic caused by the SARS-CoV-2 virus and the associated mental health
complications have renewed scholarly interest in the relationship between viral infections …
complications have renewed scholarly interest in the relationship between viral infections …
Advancing insights into virus-induced neurodevelopmental disorders through human brain organoid modelling
Human neurodevelopment is a complex process vulnerable to disruptions, particularly
during the prenatal period. Maternal viral infections represent a significant environmental …
during the prenatal period. Maternal viral infections represent a significant environmental …
[HTML][HTML] Human brain organoid: trends, evolution, and remaining challenges
Advanced brain organoids provide promising platforms for deciphering the cellular and
molecular processes of human neural development and diseases. Although various studies …
molecular processes of human neural development and diseases. Although various studies …
Transcriptomic profiling of thymic dysregulation and viral tropism after neonatal roseolovirus infection
A Belean, E Xue, B Cisneros, EDO Roberson… - Frontiers in …, 2024 - frontiersin.org
Introduction Herpesviruses, including the roseoloviruses, have been linked to autoimmune
disease. The ubiquitous and chronic nature of these infections have made it difficult to …
disease. The ubiquitous and chronic nature of these infections have made it difficult to …
The dangers of rubella virus
Brain Development: The dangers of rubella virus | eLife Skip to Content eLife logo eLife
home page Menu Home Magazine Community About Search Alerts Submit your research …
home page Menu Home Magazine Community About Search Alerts Submit your research …
The path to eradication of rubella
SE Reef, JP Icenogle, SA Plotkin - Vaccine, 2023 - Elsevier
Since 1969, rubella and its harmful effect on fetuses infected in utero can be prevented by
rubella vaccine, usually given in combination with measles vaccine. The rubella vaccine is …
rubella vaccine, usually given in combination with measles vaccine. The rubella vaccine is …
Dissecting the neurotropism and neurovirulence of MPXV using human stem cell-based models
Mpox, formerly known as monkeypox, is a zoonotic illness of international concern that can
lead to severe disease including neurological sequelae. However, it remains unclear what …
lead to severe disease including neurological sequelae. However, it remains unclear what …