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Passive, active and endogenous organ-targeted lipid and polymer nanoparticles for delivery of genetic drugs
SA Dilliard, DJ Siegwart - Nature Reviews Materials, 2023 - nature.com
Genetic drugs based on nucleic acid biomolecules are a rapidly emerging class of
medicines that directly reprogramme the central dogma of biology to prevent and treat …
medicines that directly reprogramme the central dogma of biology to prevent and treat …
Understanding ligand-protected noble metal nanoclusters at work
Ligand-protected noble metal nanoclusters, commonly termed 'monolayer-protected metal
clusters'(MPCs), comprise a common set of structures with an inorganic core stabilized by an …
clusters'(MPCs), comprise a common set of structures with an inorganic core stabilized by an …
A translational framework to DELIVER nanomedicines to the clinic
Nanomedicines have created a paradigm shift in healthcare. Yet fundamental barriers still
exist that prevent or delay the clinical translation of nanomedicines. Critical hurdles …
exist that prevent or delay the clinical translation of nanomedicines. Critical hurdles …
The crown and the scepter: roles of the protein corona in nanomedicine
Engineering nanomaterials are increasingly considered promising and powerful biomedical
tools or devices for imaging, drug delivery, and cancer therapies, but few nanomaterials …
tools or devices for imaging, drug delivery, and cancer therapies, but few nanomaterials …
Protein corona: Friend or foe? Co-opting serum proteins for nanoparticle delivery
For systemically delivered nanoparticles to reach target tissues, they must first circulate long
enough to reach the target and extravasate there. A challenge is that the particles end up …
enough to reach the target and extravasate there. A challenge is that the particles end up …
Toxicity of nanomaterials: Exposure, pathways, assessment, and recent advances
Growth in production of manufactured goods and the use of nanomaterials in consumer
products has mounted in the past few decades. Nanotoxicology or toxicity assessment of …
products has mounted in the past few decades. Nanotoxicology or toxicity assessment of …
Rational design of polymeric micelles for targeted therapeutic delivery
Polymeric micellar drug carriers have emerged as effective tools to enhance the solubility
and bioavailability of hydrophobic drugs. These micelles possess a nano size structure that …
and bioavailability of hydrophobic drugs. These micelles possess a nano size structure that …
Understanding cellular interactions with nanomaterials: Towards a rational design of medical nanodevices
Biomedical applications increasingly require fully characterized new nanomaterials. There is
strong evidence showing that nanomaterials not only interact with cells passively but also …
strong evidence showing that nanomaterials not only interact with cells passively but also …
[HTML][HTML] Exploring the therapeutic potential of Hibiscus rosa sinensis synthesized cobalt oxide (Co3O4-NPs) and magnesium oxide nanoparticles (MgO-NPs)
Herein, we present a green, economic and ecofriendly protocol for synthesis of cobalt oxide
(Co 3 O 4-NPs) and magnesium oxide nanoparticles (MgO-NPs) for multifaceted biomedical …
(Co 3 O 4-NPs) and magnesium oxide nanoparticles (MgO-NPs) for multifaceted biomedical …
Protein nanoparticle charge and hydrophobicity govern protein corona and macrophage uptake
SM Pustulka, K Ling, SL Pish… - ACS Applied Materials & …, 2020 - ACS Publications
Protein nanoparticles are biomaterials composed entirely of proteins, with the protein
sequence and structure determining the nanoparticle physicochemical properties. Upon …
sequence and structure determining the nanoparticle physicochemical properties. Upon …