Force spectroscopy of single cells using atomic force microscopy
Physical forces and mechanical properties have critical roles in cellular function, physiology
and disease. Over the past decade, atomic force microscopy (AFM) techniques have …
and disease. Over the past decade, atomic force microscopy (AFM) techniques have …
Atomic force microscopy-based force spectroscopy and multiparametric imaging of biomolecular and cellular systems
During the last three decades, a series of key technological improvements turned atomic
force microscopy (AFM) into a nanoscopic laboratory to directly observe and chemically …
force microscopy (AFM) into a nanoscopic laboratory to directly observe and chemically …
Force-distance curves by atomic force microscopy
B Cappella, G Dietler - Surface science reports, 1999 - Elsevier
Atomic force microscopy (AFM) force-distance curves have become a fundamental tool in
several fields of research, such as surface science, materials engineering, biochemistry and …
several fields of research, such as surface science, materials engineering, biochemistry and …
Covalent mechanochemistry: theoretical concepts and computational tools with applications to molecular nanomechanics
J Ribas-Arino, D Marx - Chemical reviews, 2012 - ACS Publications
In the following section, we will recapitulate selected experimental milestones through the
eyes of the theoretician, which, in our opinion, significantly advanced the field of covalent …
eyes of the theoretician, which, in our opinion, significantly advanced the field of covalent …
Detection and localization of single molecular recognition events using atomic force microscopy
Because of its piconewton force sensitivity and nanometer positional accuracy, the atomic
force microscope (AFM) has emerged as a powerful tool for exploring the forces and the …
force microscope (AFM) has emerged as a powerful tool for exploring the forces and the …
Dynamic force spectroscopy of single DNA molecules
T Strunz, K Oroszlan, R Schäfer… - Proceedings of the …, 1999 - pnas.org
To explore the analytic relevance of unbinding force measurements between
complementary DNA strands with an atomic force microscope, we measured the forces to …
complementary DNA strands with an atomic force microscope, we measured the forces to …
Force probing surfaces of living cells to molecular resolution
Biological processes rely on molecular interactions that can be directly measured using
force spectroscopy techniques. Here we review how atomic force microscopy can be applied …
force spectroscopy techniques. Here we review how atomic force microscopy can be applied …
Single-molecule experiments in biological physics: methods and applications
F Ritort - Journal of Physics: Condensed Matter, 2006 - iopscience.iop.org
I review single-molecule experiments (SMEs) in biological physics. Recent technological
developments have provided the tools to design and build scientific instruments of high …
developments have provided the tools to design and build scientific instruments of high …
Unfolding pathways of individual bacteriorhodopsins
F Oesterhelt, D Oesterhelt, M Pfeiffer, A Engel… - Science, 2000 - science.org
Atomic force microscopy and single-molecule force spectroscopy were combined to image
and manipulate purple membrane patches from Halobacterium salinarum. Individual …
and manipulate purple membrane patches from Halobacterium salinarum. Individual …
Proteoglycans of the extracellular environment: clues from the gene and protein side offer novel perspectives in molecular diversity and function
RV Iozzo, AD Murdoch - The FASEB Journal, 1996 - Wiley Online Library
This review focuses on the extracellular proteoglycans. Special emphasis is placed on the
structural features of their protein cores, their gene organization, and their transcriptional …
structural features of their protein cores, their gene organization, and their transcriptional …