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Chemistries of bifunctional PROTAC degraders
C Cao, M He, L Wang, Y He, Y Rao - Chemical Society Reviews, 2022 - pubs.rsc.org
Proteolysis targeting chimeras (PROTACs) technology is a novel and promising therapeutic
strategy using small molecules to induce ubiquitin-dependent degradation of proteins. It has …
strategy using small molecules to induce ubiquitin-dependent degradation of proteins. It has …
Photoresponsive supramolecular polymers: from light‐controlled small molecules to smart materials
Photoresponsive supramolecular polymers are well‐organized assemblies based on highly
oriented and reversible noncovalent interactions containing photosensitive molecules as (co …
oriented and reversible noncovalent interactions containing photosensitive molecules as (co …
Rational design in photopharmacology with molecular photoswitches
Photopharmacology is an attractive approach for achieving targeted drug action with the use
of light. In photopharmacology, molecular photoswitches are introduced into the structure of …
of light. In photopharmacology, molecular photoswitches are introduced into the structure of …
Photoswitchable diarylethenes: from molecular structures to biological applications
Z Li, X Zeng, C Gao, J Song, F He, T He, H Guo… - Coordination Chemistry …, 2023 - Elsevier
Diarylethene (DAE) photoswitches, known for their reversible photoinduced cyclization and
cycloreversion reactions, have shown great promise in various fields such as optical data …
cycloreversion reactions, have shown great promise in various fields such as optical data …
Proteolysis-targeting chimeras (PROTACs) in cancer therapy
X Li, W Pu, Q Zheng, M Ai, S Chen, Y Peng - Molecular cancer, 2022 - Springer
Proteolysis-targeting chimeras (PROTACs) are engineered techniques for targeted protein
degradation. A bifunctional PROTAC molecule with two covalently-linked ligands recruits …
degradation. A bifunctional PROTAC molecule with two covalently-linked ligands recruits …
Molecular photoswitches in aqueous environments
Molecular photoswitches enable dynamic control of processes with high spatiotemporal
precision, using light as external stimulus, and hence are ideal tools for different research …
precision, using light as external stimulus, and hence are ideal tools for different research …
[HTML][HTML] Functional polymer materials for modern marine biofouling control
Marine biofouling is a well-known massive problem: within the shortest time, ship hulls and
other man-made submerged surfaces are inevitably populated by various marine …
other man-made submerged surfaces are inevitably populated by various marine …
Advanced stimuli-responsive membranes for smart separation
T Huang, Z Su, K Hou, J Zeng, H Zhou… - Chemical Society …, 2023 - pubs.rsc.org
Membranes have been extensively studied and applied in various fields owing to their high
energy efficiency and small environmental impact. Further conferring membranes with …
energy efficiency and small environmental impact. Further conferring membranes with …
Visible-to-NIR-light activated release: from small molecules to nanomaterials
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …
[HTML][HTML] Spiropyran-based advanced photoswitchable materials: A fascinating pathway to the future stimuli-responsive devices
Recent years have witnessed tremendous progress and developments of the
photoswitchable spiropyran-based polymers, owing to distinctive and particular …
photoswitchable spiropyran-based polymers, owing to distinctive and particular …