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Maternal plasma DNA sequencing reveals the genome-wide genetic and mutational profile of the fetus
Cell-free fetal DNA is present in the plasma of pregnant women. It consists of short DNA
fragments among primarily maternally derived DNA fragments. We sequenced a maternal …
fragments among primarily maternally derived DNA fragments. We sequenced a maternal …
Digital PCR for the molecular detection of fetal chromosomal aneuploidy
YMD Lo, FMF Lun, KCA Chan, NBY Tsui… - Proceedings of the …, 2007 - pnas.org
Trisomy 21 is the most common reason that women opt for prenatal diagnosis. Conventional
prenatal diagnostic methods involve the sampling of fetal materials by invasive procedures …
prenatal diagnostic methods involve the sampling of fetal materials by invasive procedures …
Noninvasive prenatal diagnosis of hemophilia by microfluidics digital PCR analysis of maternal plasma DNA
NBY Tsui, RA Kadir, KCA Chan, C Chi… - Blood, The Journal …, 2011 - ashpublications.org
Hemophilia is a bleeding disorder with X-linked inheritance. Current prenatal diagnostic
methods for hemophilia are invasive and pose a risk to the fetus. Cell-free fetal DNA …
methods for hemophilia are invasive and pose a risk to the fetus. Cell-free fetal DNA …
Fetal genomic analysis from a maternal biological sample
YMD Lo, KC Chan, WKR Chiu, C Cantor - US Patent 8,467,976, 2013 - Google Patents
2012-05-03 Assigned to THE CHINESE UNIVERSITY OF HONG KONG reassignment THE
CHINESE UNIVERSITY OF HONG KONG ASSIGNMENT OF ASSIGNORS INTEREST (SEE …
CHINESE UNIVERSITY OF HONG KONG ASSIGNMENT OF ASSIGNORS INTEREST (SEE …
Uses of cell free fetal DNA in maternal circulation
M Hill, AN Barrett, H White, LS Chitty - Best practice & research Clinical …, 2012 - Elsevier
For over a decade, researchers have focused their attention on the development of non-
invasive prenatal diagnosis tests based on cell-free fetal DNA circulating in maternal blood …
invasive prenatal diagnosis tests based on cell-free fetal DNA circulating in maternal blood …
Theoretical design and analysis of multivolume digital assays with wide dynamic range validated experimentally with microfluidic digital PCR
This paper presents a protocol using theoretical methods and free software to design and
analyze multivolume digital PCR (MV digital PCR) devices; the theory and software are also …
analyze multivolume digital PCR (MV digital PCR) devices; the theory and software are also …
Methods and compositions for determining ploidy
2017-11-13 Assigned to NATERA, INC. reassignment NATERA, INC. ASSIGNMENT OF
ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: KIRKIZLAR …
ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: KIRKIZLAR …
Methods for non-invasive prenatal ploidy calling
M Rabinowitz, G Gemelos, M Banjevic, A Ryan… - US Patent …, 2022 - Google Patents
2015-06-22 Assigned to GENE SECURITY NETWORK INC. reassignment GENE
SECURITY NETWORK INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
SECURITY NETWORK INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
Detecting mutations and ploidy in chromosomal segments
J Babiarz, TP Constantin, LA Eubank… - US Patent …, 2022 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
57221528&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
57221528&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
Detecting mutations and ploidy in chromosomal segments
J Babiarz, TP Constantin, LA Eubank… - US Patent …, 2022 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
57221528&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
57221528&utm_source= google_patent&utm_medium= platform_link&utm_campaign …