β-lactam antibiotics: An overview from a medicinal chemistry perspective

LM Lima, BNM da Silva, G Barbosa… - European journal of …, 2020 - Elsevier
Abstract β-Lactam antibiotics are one of the most relevant drug classes of antibacterial
agents worldwide. The discovery and the market of first β-lactam antibiotic (Penicillin G) is a …

Metal-based nanoparticles: Antibacterial mechanisms and biomedical application

D Franco, G Calabrese, SPP Guglielmino, S Conoci - Microorganisms, 2022 - mdpi.com
The growing increase in antibiotic-resistant bacteria has led to the search for new
antibacterial agents capable of overcoming the resistance problem. In recent years …

A broad-spectrum antibiotic adjuvant reverses multidrug-resistant Gram-negative pathogens

M Song, Y Liu, X Huang, S Ding, Y Wang, J Shen… - Nature …, 2020 - nature.com
The rapid emergence and dissemination of multidrug-resistant (MDR) bacterial pathogens
pose a serious threat to global healthcare. One particular concern is the carbapenem …

Critical green routing synthesis of silver NPs using jasmine flower extract for biological activities and photocatalytical degradation of methylene blue

M Aravind, A Ahmad, I Ahmad, M Amalanathan… - Journal of …, 2021 - Elsevier
Herin, we prepared silver NPs using jasmine flower extract. The green synthesis process
reports a eco-friendly, nontoxic, cost-effective and simple approach to the synthesis of metal …

Recent innovations in bacterial infection detection and treatment

C Deusenbery, Y Wang, A Shukla - ACS Infectious Diseases, 2021 - ACS Publications
Bacterial infections are a major threat to human health, exacerbated by increasing antibiotic
resistance. These infections can result in tremendous morbidity and mortality, emphasizing …

[HTML][HTML] Towards applications of bioentities@ MOFs in biomedicine

MJ Velásquez-Hernández, M Linares-Moreau… - Coordination Chemistry …, 2021 - Elsevier
Metal–organic frameworks (MOFs) combined with biomacromolecules, viruses and cells
have emerged as novel biocomposites for application to drug delivery, biosensing …

Impact of reactive oxygen species on cell activity and structural integrity of Gram-positive and Gram-negative bacteria in electrochemical disinfection system

J Zhang, P Su, H Chen, M Qiao, B Yang… - Chemical Engineering …, 2023 - Elsevier
High efficiency, eco-friendly, and without disinfection byproducts rendered the hydroxyl
radical-dominated electrochemical process a promising disinfection technology. Inconsistent …

Antimicrobial peptides: mechanisms of action and resistance

B Bechinger, SU Gorr - Journal of dental research, 2017 - journals.sagepub.com
More than 40 antimicrobial peptides and proteins (AMPs) are expressed in the oral cavity.
These AMPs have been organized into 6 functional groups, 1 of which, cationic AMPs, has …

Membrane active antimicrobial peptides: translating mechanistic insights to design

J Li, JJ Koh, S Liu, R Lakshminarayanan… - Frontiers in …, 2017 - frontiersin.org
Antimicrobial peptides (AMPs) are promising next generation antibiotics that hold great
potential for combating bacterial resistance. AMPs can be both bacteriostatic and …

Membrane targeting cationic antimicrobial peptides

D Ciumac, H Gong, X Hu, JR Lu - Journal of colloid and interface science, 2019 - Elsevier
Many short cationic peptides are amphiphilic and are often termed antimicrobial peptides
(AMPs) as they can kill various microorganisms. These AMPs have largely been discovered …