Database resources of the national center for biotechnology information

EW Sayers, EE Bolton, JR Brister… - Nucleic acids …, 2022 - academic.oup.com
Abstract The National Center for Biotechnology Information (NCBI) produces a variety of
online information resources for biology, including the GenBank® nucleic acid sequence …

UCSF ChimeraX: Structure visualization for researchers, educators, and developers

EF Pettersen, TD Goddard, CC Huang… - Protein …, 2021 - Wiley Online Library
UCSF ChimeraX is the next‐generation interactive visualization program from the Resource
for Biocomputing, Visualization, and Informatics (RBVI), following UCSF Chimera. ChimeraX …

Computational approaches to therapeutic antibody design: established methods and emerging trends

RA Norman, F Ambrosetti, AMJJ Bonvin… - Briefings in …, 2020 - academic.oup.com
Antibodies are proteins that recognize the molecular surfaces of potentially noxious
molecules to mount an adaptive immune response or, in the case of autoimmune diseases …

ClinVar: improving access to variant interpretations and supporting evidence

MJ Landrum, JM Lee, M Benson, GR Brown… - Nucleic acids …, 2018 - academic.oup.com
Abstract ClinVar (https://www. ncbi. nlm. nih. gov/clinvar/) is a freely available, public archive
of human genetic variants and interpretations of their significance to disease, maintained at …

UCSF ChimeraX: Meeting modern challenges in visualization and analysis

TD Goddard, CC Huang, EC Meng… - Protein …, 2018 - Wiley Online Library
UCSF ChimeraX is next‐generation software for the visualization and analysis of molecular
structures, density maps, 3D microscopy, and associated data. It addresses challenges in …

Expasy, the Swiss Bioinformatics Resource Portal, as designed by its users

S Duvaud, C Gabella, F Lisacek… - Nucleic acids …, 2021 - academic.oup.com
Abstract The SIB Swiss Institute of Bioinformatics (https://www. sib. swiss) creates, maintains
and disseminates a portfolio of reliable and state-of-the-art bioinformatics services and …

The BioGRID interaction database: 2019 update

R Oughtred, C Stark, BJ Breitkreutz, J Rust… - Nucleic acids …, 2019 - academic.oup.com
Abstract The Biological General Repository for Interaction Datasets (BioGRID:
https://thebiogrid. org) is an open access database dedicated to the curation and archival …

The MEROPS database of proteolytic enzymes, their substrates and inhibitors in 2017 and a comparison with peptidases in the PANTHER database

ND Rawlings, AJ Barrett, PD Thomas… - Nucleic acids …, 2018 - academic.oup.com
Abstract The MEROPS database (http://www. ebi. ac. uk/merops/) is an integrated source of
information about peptidases, their substrates and inhibitors. The hierarchical classification …

Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates

J Damas, GM Hughes, KC Keough… - Proceedings of the …, 2020 - National Acad Sciences
The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
the cause of COVID-19. The main receptor of SARS-CoV-2, angiotensin I converting enzyme …

Expansion of the Gene Ontology knowledgebase and resources

Gene Ontology Consortium - Nucleic acids research, 2017 - academic.oup.com
Abstract The Gene Ontology (GO) is a comprehensive resource of computable knowledge
regarding the functions of genes and gene products. As such, it is extensively used by the …