Two different perspectives have informed efforts to explain the link between the brain and
behaviour. One approach seeks to identify neural circuit elements that carry out specific …

Neuroscientists today can measure activity from more neurons than ever before, and are
facing the challenge of connecting these brain-wide neural recordings to computation and …

Cognitive control guides behaviour by controlling what, when, and how information is
represented in the brain. For example, attention controls sensory processing; top-down …

Working memory is the fundamental function by which we break free from reflexive input-
output reactions to gain control over our own thoughts. It has two types of mechanisms …

A major shift is happening within neurophysiology: a population doctrine is drawing level
with the single-neuron doctrine that has long dominated the field. Population-level ideas …

Recent theoretical models propose that working memory is mediated by rapid transitions
in'activity-silent'neural states (for example, short-term synaptic plasticity). According to the …

Short-term memories link events separated in time, such as past sensation and future
actions. Short-term memories are correlated with slow neural dynamics, including selective …

Persistent activity generated in the PFC during the delay period of working memory tasks
represents information about stimuli held in memory and determines working memory …

Persistent spiking has been thought to underlie working memory (WM). However, virtually all
of the evidence for this comes from studies that averaged spiking across time and across …

Persistent neuronal spiking has long been considered the mechanism underlying working
memory, but recent proposals argue for alternative 'activity-silent'substrates. Using monkey …