With the development of nanotechnology, nanomedicines are widely used in tumor therapy.
However, biological barriers in the delivery of nanoparticles still limit their application in …

Cancer is one of the main causes of death worldwide. To date, and despite the advances in
conventional treatment options, therapy in cancer is still far from optimal due to the non …

The earliest example of in vivo expression of exogenous mRNA is by direct intramuscular
injection in mice without the aid of a delivery vehicle. The current state of the art for …

Owing to the inherent shortcomings of traditional therapeutic drugs in terms of inadequate
therapeutic efficacy and toxicity in clinical treatment, nanomedicine designs have received …

Cardiovascular disease (CVD) is a major global health issue with high mortality and
morbidity rates. With the advances in nanotechnology, nanoparticles are receiving …

Cancer immunotherapy has tremendous promise, but it has yet to be clinically applied in a
wider variety of tumor situations. Many therapeutic combinations are envisaged to improve …

Now, metal oxide nanoparticles (NPs) are considered to have important scientific
applications. Considering the toxicity of these nanomaterials is an important research issue …

Cancer is a critical cause of global human death. Not only are complex approaches to
cancer prognosis, accurate diagnosis, and efficient therapeutics concerned, but post …

We developed a simulation methodology on the basis of machine learning techniques for
simulation of pharmaceutical solubility in a supercritical solvent, ie, CO 2 with the …

Irinotecan (IRT), a classic clinical chemotherapeutic agent for treating colorectal cancer, has
been found to induce immunogenic cell death (ICD) while exerting cytotoxicity in tumor cells …