Pt (II)-thiocarbohydrazone complex as cytotoxic agent and apoptosis inducer in Caov-3 and HT-29 Cells through the P53 and caspase-8 pathways

AA Ibrahim, MM Kareem, TH Al-Noor, T Al-Muhimeed… - Pharmaceuticals, 2021 - mdpi.com
In this study, a platinum (II) complex ([Pt (H2L)(PPh3)] complex) containing a
thiocarbohydrazone as the ligand was tested as an anti-proliferative agent against ovarian …

Soft and condensed nanoparticles and nanoformulations for cancer drug delivery and repurpose

W Yang, H Veroniaina, X Qi, P Chen, F Li… - Advanced …, 2020 - Wiley Online Library
Drug repurpose or reposition has been recently recognized as a high‐performance strategy
for develo** therapeutic agents for cancer treatment. This approach can significantly …

Novel azo pyridone dyes based on dihydropyrimidinone skeleton: Synthesis, DFT study and anticancer activity

JD Tadić, JM Lađarević, ŽJ Vitnik, VD Vitnik… - Dyes and …, 2021 - Elsevier
Seven novel azo dyes with 2-pyridone and dihydropyrimidinone moieties have been
synthesized and thoroughly characterized. The azo-hydrazone tautomerism has been …

Bioactivity, molecular docking and anticancer behavior of pyrrolidine based Pt (II) complexes: Their kinetics, DNA and BSA binding study by spectroscopic methods

SK Tarai, S Mandal, R Bhaduri, A Pan, P Biswas… - … Acta Part A: Molecular …, 2023 - Elsevier
Abstract The complex [Pt (AEP) Cl 2]; C-1 (where, AEP= 1-(2-Aminoethyl) pyrrolidine) and its
hydrolyzed diaqua form cis-[Pt (AEP)(H 2 O) 2] 2+; C-2 were synthesized for their bioactivity …

A Urea-Functionalized Chemoreceptor for Expeditious Chromogenic Recognition of Toxic Industrial Pollutants Cu2+ and CN from Real Water Sources and …

S Paul, R Das, M Seth, H Hirani… - Industrial & …, 2020 - ACS Publications
A urea-functionalized chemoreceptor 1, 5-bis (2, 4-dinitrophenyl) carbonohydrazide (BDC)
with versatile applications has been reported in this work. BDC displayed ditopic sensitivity …

Heterodinuclear Cu–Gd (3d-4f) complex with di-compartmental Schiff base ligand in biological activity: Synthesis, crystal structure, catecholase activity and DNA & …

E Keshavarzian, Z Asadi, M Poupon, M Dusek… - Journal of Molecular …, 2022 - Elsevier
Abstract A dinuclear Cu II-Gd III Schiff base complex (a di-compartmental Schiff base ligand
derived from o-vanillin) nominated as: 1, 3-propanediyl-bis (2-iminomethylene-6-methoxy …

Cytotoxic effect of green synthesized silver nanoparticles in MCF7 and MDA-MB-231 human breast cancer cells in vitro

A Bandyopadhyay, B Roy, P Shaw, P Mondal… - The Nucleus, 2020 - Springer
With the incessant rise in the cancer burden worldwide it is a dire need to develop
anticancer agents that will offer negligible or no side effects and at the same time will be …

Heteroleptic complexes of hydrazone Scaffold of picolinoyl N-oxide and 2, 4 dihydroxy phenyl moieties; evaluation of antioxidant activity, DNA and protein binding …

S Deepa, N Mathangi, R Mudavath, I Shekhar… - Inorganica Chimica …, 2025 - Elsevier
The present study deals with design and synthesis of new mononuclear Cu (II), Co (II), Ni (II)
and Zn (II) metal complexes of hydrazone of 2-(2-(2, 4-dihydroxybenzylidene) …

Role of π-conjugation on the coordination behaviour, substitution kinetics, DNA/BSA interactions, and in vitro cytotoxicity of carboxamide palladium (ii) complexes

RO Omondi, NRS Sibuyi, AO Fadaka, M Meyer… - Dalton …, 2021 - pubs.rsc.org
Treatments of N-(pyridin-2-ylmethyl) pyrazine-2-carboxamide (L1), N-(quinolin-8-yl)
pyrazine-2-carboxamide (L2), N-(quinolin-8-yl) picolinamide (L3) and N-(quinolin-8-yl) …

Anticancer activity and biomolecular interaction of Pt (II) complexes: Their synthesis, characterisation and DFT study

S Mandal, VP Reddy B, I Mitra… - Applied …, 2022 - Wiley Online Library
Abstract Cis‐[Pt (TEEDA) Cl2]; 1 (where TEEDA= N, N, N′‐triethylethylenediamine) was
synthesised, and its SCXRD structure was determined. Complex 1 crystallises in the …