Arginine derivatives in cerebrovascular diseases: mechanisms and clinical implications

GM Grosse, E Schwedhelm, H Worthmann… - International Journal of …, 2020 - mdpi.com
The amino acid L-arginine serves as substrate for the nitric oxide synthase which is crucial
in vascular function and disease. Derivatives of arginine, such as asymmetric (ADMA) and …

Evaluation of endothelial glycocalyx injury biomarkers in feline hemotropic mycoplasmosis

M Ider, C Ceylan, A Naseri, O Ceylan, MK Durgut… - Scientific Reports, 2024 - nature.com
The present study aimed to investigate endothelial glycocalyx (eGCx) damage in cats with
feline hemotropic mycoplasmosis caused by Mycoplasma haemofelis using selected …

Asymmetric dimethylarginine and critical illness

SJH Brinkmann, MC de Boer, N Buijs… - Current Opinion in …, 2014 - journals.lww.com
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The role of asymmetric dimethylarginine (ADMA) in COVID-19: association with respiratory failure and predictive role for outcome

E Sozio, J Hannemann, M Fabris, A Cifù, A Ripoli… - Scientific Reports, 2023 - nature.com
We aimed to assess the potential role of Asymmetric dimethylarginine (ADMA) in
conditioning respiratory function and pulmonary vasoregulation during Severe Acute …

Symmetrical (SDMA) and asymmetrical dimethylarginine (ADMA) in sepsis: high plasma levels as combined risk markers for sepsis survival

MS Winkler, A Nierhaus, G Rösler, S Lezius… - Critical Care, 2018 - Springer
Background Nitric oxide (NO) regulates processes involved in sepsis progression, including
vascular and immune function. NO is generated by nitric oxide synthases (NOS) from L …

Asymmetric dimethylarginine, endothelial nitric oxide bioavailability and mortality in sepsis

JS Davis, CJ Darcy, TW Yeo, C Jones, YR McNeil… - PloS one, 2011 - journals.plos.org
Background Plasma concentrations of asymmetric dimethylarginine (ADMA), an
endogenous inhibitor of nitric oxide synthase, are raised in patients with chronic vascular …

Elevated asymmetric dimethylarginine levels predict short-and long-term mortality risk in critically ill patients

A Koch, R Weiskirchen, J Kunze, H Dückers… - Journal of Critical …, 2013 - Elsevier
Objective Serum concentrations of asymmetric dimethylarginine (ADMA), an endogenous
inhibitor of nitric oxide synthase, may contribute to endothelial dysfunction and organ failure …

Changes in nitric oxide inhibitors and mortality in critically ill patients: a cohort study

KM Mortensen, TS Itenov, J Stensballe, T Hillig… - Annals of Intensive …, 2024 - Springer
Background Optimal balance between macro-and microcirculation in critically ill patients is
crucial for ensuring optimal organ perfusion. Nitric oxide (NO) is a regulator of vascular …

Regulation and prognostic relevance of symmetric dimethylarginine serum concentrations in critical illness and sepsis

A Koch, R Weiskirchen, J Bruensing… - Mediators of …, 2013 - Wiley Online Library
In systemic inflammation and sepsis, endothelial activation and microvascular dysfunction
are characteristic features that promote multiorgan failure. As symmetric dimethylarginine …

Intact FGF23 and α‐klotho during acute inflammation/sepsis in CKD patients

E Dounousi, C Torino, P Pizzini… - European journal of …, 2016 - Wiley Online Library
Background High FGF23 and low α‐Klotho levels associate with systemic inflammation and
reduced nitric oxide (NO) bioavailability, but the dynamics of this relationship in patients with …