Accelerating growth and global expansion of antimicrobial resistance has deepened the
need for discovery of novel antimicrobial agents. Antimicrobial peptides have clear …

Water‐membrane soluble protein and peptide toxins are used in the defense and offense
systems of all organisms, including plants and humans. A major group includes …

Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) were
used to examine the ultrastructural changes in bacteria induced by antimicrobial peptides …

Macrocyclic natural products have been recognized and utilized as new platforms for
designing drugs in pharmaceutical research because the constrained three-dimensional …

Synthetic hemigramicidin S-peptidyl TEMPO conjugates are effectively delivered into cells
and mitochondria, where they act as electron scavengers and exert protection against …

Oxidative damage to various cellular constituents (such as, proteins and lipids) mediated by
reactive oxygen species (ROS) is thought to be an important mechanism underlying the …

Antimicrobial peptides are present in organisms spanning virtually every kingdom, and
employ sophisticated mechanisms to exert rapid microbicidal action consistent with their key …

Gramicidin S (GS), one of the oldest commercially used peptide antibiotics, is known for its
robust antibacterial activity against both Gram-positive and Gram-negative bacterial strains …

Hydrophobic interactions govern specificity for natural antimicrobial peptides. No such
relationship has been established for synthetic peptoids that mimic antimicrobial peptides …

Gramicidin S (GS) is a 10‐residue cyclic β‐sheet peptide with lytic activity against the
membranes of both microbial and human cells, ie it possesses little to no biologic specificity …