Noble metals in medicine: Latest advances
History shows that metal-based drugs and remedies have been known and used since very
ancient times. For example, silver was employed in the treatment of wounds and ulcers …
ancient times. For example, silver was employed in the treatment of wounds and ulcers …
Update on metal N-heterocyclic carbene complexes as potential anti-tumor metallodrugs
W Liu, R Gust - Coordination Chemistry Reviews, 2016 - Elsevier
The clinical success of platinum-based chemotherapeutic agents was of enormous impact
on the discovery of novel metal N-heterocyclic carbene (NHC) complexes as potential anti …
on the discovery of novel metal N-heterocyclic carbene (NHC) complexes as potential anti …
Recent developments in the medicinal applications of silver-NHC complexes and imidazolium salts
NA Johnson, MR Southerland, WJ Youngs - Molecules, 2017 - mdpi.com
Because of their great structural diversity and multitude of chemical properties, N-
heterocyclic carbenes (NHCs) have been utilized in a variety of capacities. Most recently …
heterocyclic carbenes (NHCs) have been utilized in a variety of capacities. Most recently …
Silver complexes as anticancer agents: A perspective review
SK Raju, A Karunakaran, S Kumar, P Sekar… - German Journal of …, 2022 - gjpb.de
Metal complexes gained more attention in the medical field, particularly cancer treatment,
due to their enhanced potential and redox ability. These complexes exhibited more …
due to their enhanced potential and redox ability. These complexes exhibited more …
Synthesis, characterization and bioactivities of dative donor ligand N-heterocyclic carbene (NHC) precursors and their Ag (I) NHC coordination compounds
This study contains the synthesis of N-phthalimidomethyl-substituted NHC precursors and
their Ag (I) NHC coordination compounds. The NHC precursors were synthesized from the 1 …
their Ag (I) NHC coordination compounds. The NHC precursors were synthesized from the 1 …
Functionalized benzimidazole scaffolds: privileged heterocycle for drug design in therapeutic medicine
Benzimidazole derivatives are crucial structural scaffolds found in diverse libraries of
biologically active compounds which are therapeutically useful agents in drug discovery and …
biologically active compounds which are therapeutically useful agents in drug discovery and …
Human colon cancer targeted pro-apoptotic, anti-metastatic and cytostatic effects of binuclear Silver (I)–N-Heterocyclic carbene (NHC) complexes
The current mechanistic study was conducted to explore the effects of increased lipophilicity
of binuclear silver (I)–NHC complexes on cytotoxicity. Two new silver (I)–N-Heterocyclic …
of binuclear silver (I)–NHC complexes on cytotoxicity. Two new silver (I)–N-Heterocyclic …
[HTML][HTML] Synthesis, structural characterization of silver (I)-NHC complexes and their antimicrobial, antioxidant and antitumor activities
To prepare a novel series of silver (I) complexes, the interaction of benzimidazolium salts
having their two nitrogen atoms substituted by bulky groups with Ag 2 O in DMF has been …
having their two nitrogen atoms substituted by bulky groups with Ag 2 O in DMF has been …
Novel gold (I)–and gold (III)–N-heterocyclic carbene complexes: synthesis and evaluation of their anticancer properties
A novel Au (III)–N-heterocyclic carbene organometallic complex supported by two N-
heterocyclic carbene (NHC) ligands was synthesized from Au (SMe2) Cl and 1-methyl-2 …
heterocyclic carbene (NHC) ligands was synthesized from Au (SMe2) Cl and 1-methyl-2 …
Green synthesis of selenium-N-heterocyclic carbene compounds: Evaluation of antimicrobial and anticancer potential
Three benzimidazolium salts (III-V) and respective selenium adducts (VI-VIII) were designed,
synthesized and characterized by various analytical techniques (FT-IR and NMR 1 H, 13 C) …
synthesized and characterized by various analytical techniques (FT-IR and NMR 1 H, 13 C) …