A review on the crosstalk between non-coding RNAs and the cGAS-STING signaling pathway

Z **ong, Y Wang, Z Li, C Li, C Tu, Z Li - International Journal of Biological …, 2024 - Elsevier
In the innate immune system, the cyclic GMP-AMP synthase (cGAS)-interferon gene
stimulator (STING) pathway activates the type I interferon (IFN) response and the NF-κB …

RNA interactome of hypervirulent Klebsiella pneumoniae reveals a small RNA inhibitor of capsular mucoviscosity and virulence

K Wu, X Lin, Y Lu, R Dong, H Jiang… - Nature …, 2024 - nature.com
Abstract Hypervirulent Klebsiella pneumoniae (HvKP) is an emerging bacterial pathogen
causing invasive infection in immune-competent humans. The hypervirulence is strongly …

ProQ-associated small RNAs control motility in Vibrio cholerae

R Ghandour, D Devlitsarov, P Popp… - Nucleic Acids …, 2024 - academic.oup.com
Gene regulation at the post-transcriptional level is prevalent in all domains of life. In bacteria,
ProQ-like proteins have emerged as important RNA chaperones facilitating RNA stability …

Slings and arrows: sRNAs mediate intragenomic competition

MJ Ferrell, CM Waters - Cell Host & Microbe, 2024 - Elsevier
Bacterial genomes are littered with exogenous: competing DNA elements. Here, Sprenger et
al. demonstrate that the Vibrio cholerae prophage VP882 modulates host functions via …

Biological Insights from RNA–RNA Interactomes in Bacteria, as Revealed by RIL-seq

A Silverman, S Melamed - High Throughput Gene Screening: Methods …, 2024 - Springer
Bacteria reside in constantly changing environments and require rapid and precise
adjustments of gene expression to ensure survival. Small regulatory RNAs (sRNAs) are a …

Phage-encoded small RNA hijacks host replication machinery to support the phage lytic cycle

A Silverman, R Nashef, R Bruner, T Noy, S Melamed - bioRxiv, 2024 - biorxiv.org
Bacteriophages (phages) significantly influence bacterial populations in their natural
environment. However, one aspect that has not been thoroughly explored in the context of …