Antimicrobial photodynamic therapy: Latest developments with a focus on combinatory strategies
R Youf, M Müller, A Balasini, F Thétiot, M Müller… - Pharmaceutics, 2021 - mdpi.com
Antimicrobial photodynamic therapy (aPDT) has become a fundamental tool in modern
therapeutics, notably due to the expanding versatility of photosensitizers (PSs) and the …
therapeutics, notably due to the expanding versatility of photosensitizers (PSs) and the …
Antimicrobial blue light: A 'Magic Bullet'for the 21st century and beyond?
Over the past decade, antimicrobial blue light (aBL) at 400− 470 nm wavelength has
demonstrated immense promise as an alternative approach for the treatment of multidrug …
demonstrated immense promise as an alternative approach for the treatment of multidrug …
Dissolving microneedle-mediated dermal delivery of itraconazole nanocrystals for improved treatment of cutaneous candidiasis
The administration of conventional dosage forms of itraconazole (ITZ) for cutaneous
candidiasis treatment is limited by its poor aqueous solubility and the deep location of …
candidiasis treatment is limited by its poor aqueous solubility and the deep location of …
Dissolving microneedle patches loaded with amphotericin B microparticles for localised and sustained intradermal delivery: Potential for enhanced treatment of …
Fungal infections affect millions of people globally and are often unreceptive to conventional
topical or oral preparations because of low drug bioavailability at the infection site, lack of …
topical or oral preparations because of low drug bioavailability at the infection site, lack of …
Antimicrobial Resistance: Is There a 'Light'at the End of the Tunnel?
In recent years, with the increases in microorganisms that express a multitude of
antimicrobial resistance (AMR) mechanisms, the threat of antimicrobial resistance in the …
antimicrobial resistance (AMR) mechanisms, the threat of antimicrobial resistance in the …
[HTML][HTML] Photoinactivation of catalase sensitizes a wide range of bacteria to ROS-producing agents and immune cells
Bacteria have evolved to cope with the detrimental effects of ROS using their essential
molecular components. Catalase, a heme-containing tetramer protein expressed universally …
molecular components. Catalase, a heme-containing tetramer protein expressed universally …
[HTML][HTML] Nanoparticle enhanced blue light therapy
As antimicrobial resistance continues to compromise the therapeutic efficacy of countless
antibiotics, the significant risk this poses to the global population is without question and …
antibiotics, the significant risk this poses to the global population is without question and …
Spectra of pathogens predict lethality of blue light photo-inactivation
DM Harris - Laser Therapy, 2023 - lasertherapyjournal.com
Whole-cell spectra of human pathogens are examined to identify species-specific
wavelengths of maximum light absorption. It is presented how these data relate to clinical …
wavelengths of maximum light absorption. It is presented how these data relate to clinical …
Managing Corneal Infections: Out with the old, in with the new?
There have been multiple reports of eye infections caused by antibiotic-resistant bacteria,
with increasing evidence of ineffective treatment outcomes from existing therapies. With …
with increasing evidence of ineffective treatment outcomes from existing therapies. With …
Effective treatment of cutaneous mold infections by antimicrobial blue light that is potentiated by quinine
Background Cutaneous mold infections commonly result from an array of traumatic injuries
that involve direct inoculation of contaminated soil into wounds. Here, we explored the use …
that involve direct inoculation of contaminated soil into wounds. Here, we explored the use …