Blood vessel formation and function in bone
KK Sivaraj, RH Adams - Development, 2016 - journals.biologists.com
In addition to their conventional role as a conduit system for gases, nutrients, waste products
or cells, blood vessels in the skeletal system play active roles in controlling multiple aspects …
or cells, blood vessels in the skeletal system play active roles in controlling multiple aspects …
Diabetes and its effect on bone and fracture healing
H Jiao, E **ao, DT Graves - Current osteoporosis reports, 2015 - Springer
Diabetes mellitus is a metabolic disorder that increases fracture risk, interferes with bone
formation, and impairs fracture healing. Type 1 diabetes mellitus (T1DM) and type 2 …
formation, and impairs fracture healing. Type 1 diabetes mellitus (T1DM) and type 2 …
Highly loaded hydroxyapatite microsphere/PLA porous scaffolds obtained by fused deposition modelling
The goal of the work was the manufacturing of hydroxyapatite microsphere/polylactic acid
(PLA) scaffolds by means of fused deposition modelling (FDM). Micrometer-sized …
(PLA) scaffolds by means of fused deposition modelling (FDM). Micrometer-sized …
Bone vasculature and bone marrow vascular niches in health and disease
J Chen, M Hendriks, A Chatzis… - Journal of Bone and …, 2020 - academic.oup.com
Bone vasculature and bone marrow vascular niches supply oxygen, nutrients, and secrete
angiocrine factors required for the survival, maintenance, and self‐renewal of stem and …
angiocrine factors required for the survival, maintenance, and self‐renewal of stem and …
Developmentally engineered callus organoid bioassemblies exhibit predictive in vivo long bone healing
Clinical translation of cell‐based products is hampered by their limited predictive in vivo
performance. To overcome this hurdle, engineering strategies advocate to fabricate tissue …
performance. To overcome this hurdle, engineering strategies advocate to fabricate tissue …
Cartilage to bone transformation during fracture healing is coordinated by the invading vasculature and induction of the core pluripotency genes
DP Hu, F Ferro, F Yang, AJ Taylor, W Chang… - …, 2017 - journals.biologists.com
Fractures heal predominantly through the process of endochondral ossification. The classic
model of endochondral ossification holds that chondrocytes mature to hypertrophy, undergo …
model of endochondral ossification holds that chondrocytes mature to hypertrophy, undergo …
Fracture healing in osteoporotic bone
As the world population rises, osteoporotic fracture is an emerging global threat to the well-
being of elderly patients. The process of fracture healing by intramembranous ossification …
being of elderly patients. The process of fracture healing by intramembranous ossification …
Tissue engineering strategies for promoting vascularized bone regeneration
S Almubarak, H Nethercott, M Freeberg, C Beaudon… - Bone, 2016 - Elsevier
This review focuses on current tissue engineering strategies for promoting vascularized
bone regeneration. We review the role of angiogenic growth factors in promoting …
bone regeneration. We review the role of angiogenic growth factors in promoting …
The impact of type 2 diabetes on bone fracture healing
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease known by the presence of
elevated blood glucose levels. Nowadays, it is perceived as a worldwide epidemic, with a …
elevated blood glucose levels. Nowadays, it is perceived as a worldwide epidemic, with a …
Rapid initiation of guided bone regeneration driven by spatiotemporal delivery of IL-8 and BMP-2 from hierarchical MBG-based scaffold
Initiation of endogenous repair mechanisms, including key steps of stem cell recruitment and
cartilage intermediate formation in endochondral ossification, is vital to regeneration of large …
cartilage intermediate formation in endochondral ossification, is vital to regeneration of large …