Poly (lactic acid) or polylactide (PLA) is the most extensively researched and utilized
biodegradable and renewable thermoplastic polyester, with potential to replace …

Biodegradable polymers have been used in biomedical applications generally, and in tissue
engineering especially, due to good physical and biological properties. Poly …

The controlled delivery of growth factors and cells within biomaterial carriers can enhance
and accelerate functional bone formation. The carrier system can be designed with pre …

Critical‐sized defects in bone, whether induced by primary tumor resection, trauma, or
selective surgery have in many cases presented insurmountable challenges to the current …

Growth factors (GFs) are signaling molecules that direct cell development by providing
biochemical cues for stem cell proliferation, migration, and differentiation. GFs play a key …

The aim of this study was to develop a 3-D construct carrying an inherent sequential growth
factor delivery system. Poly (lactic acid-co-glycolic acid)(PLGA) nanocapsules loaded with …

Abstract Poly (ε-caprolactones)(PCLs) belong to the first generation of synthetic aliphatic
polyesters. Their biodegradability motivated their extensive exploration as resorbable …

Niches regulate lineage-specific stem cell self-renewal versus differentiation in vivo and are
composed of supportive cells and extracellular matrix components arranged in a three …

Although polycationic surfaces have high antimicrobial efficacies, they suffer from high
toxicity to mammalian cells and severe surface accumulation of dead bacteria. For the first …

Integrating an advanced manufacturing technique, nanocomposite material and controlled
delivery of growth factor to form multifunctional tissue engineering scaffolds was investigated …