Triggering receptors expressed on myeloid cells (TREMs) encompass a family of cell-
surface receptors chiefly expressed by granulocytes, monocytes and tissue macrophages …

Triggering receptor expressed on myeloid cells-1 (TREM-1) is expressed on the majority of
innate immune cells and to a lesser extent on parenchymal cells. Upon activation, TREM-1 …

TREM proteins are a family of cell surface receptors that participate in diverse cell
processes, including inflammation, bone homeostasis, neurological development and …

Since the discovery of triggering receptor expressed on myeloid cells (TREM)-1 in 2000,
evidence documenting the profound ability of the TREM and TREM-like receptors to regulate …

This review summarizes recent developments in our understanding of the molecular basis of
platelet activation by two distinct types of surface receptor, the immunoglobulin GPVI, and …

Receptors carrying immunoreceptor tyrosine‐based inhibition motifs (ITIMs) in their
cytoplasmic tail control a vast array of cellular responses, ranging from autoimmunity …

Although post-ischemic inflammation induced by the innate immune response is considered
an essential step in the progression of cerebral ischemia injury, the role of triggering …

Summary The glycoprotein VI (GPVI)–FcR γ‐chain complex initiates powerful activation of
platelets by the subendothelial matrix proteins collagen and laminin through an …

Osteoclasts are terminally differentiated leukocytes that erode the mineralized bone matrix.
Osteoclastogenesis requires costimulatory receptor signaling through adaptors containing …

The triggering receptor expressed on myeloid cells 1 (TREM-1) plays an important role in
the innate immune response related to severe infections and sepsis. Modulation of TREM-1 …