Controlling the conformation and activity of biomolecules in a reversible manner is a
fascinating challenge (1-3) that has an outstanding potential for the study of and interference …

The photoisomerization of azobenzene has been known for almost 75 years but only
recently has this process been widely applied to biological systems. The central challenge of …

The photoisomerization of azobenzenes provides a general means for the photocontrol of
molecular structure and function. For applications in vivo, however, the wavelength of …

Transmembrane receptors allow a cell to communicate with its environment in response to a
variety of input signals. These can be changes in the concentration of ligands (eg hormones …

Infrared spectroscopy has played an instrumental role in the study of a wide variety of
biological questions. However, in many cases, it is impossible or difficult to rely on the …

Controlling the activity of proteins with azobenzene photoswitches is a potent tool for
manipulating their biological function. With the help of light, it is possible to change binding …

Wordom is a versatile, user‐friendly, and efficient program for manipulation and analysis of
molecular structures and dynamics. The following new analysis modules have been added …

Liquid–liquid phase separation (LLPS) is involved in both physiological and pathological
processes. The intrinsically disordered protein Tau and its K18 construct can undergo LLPS …

Vibrational spectroscopy provides a direct route to the physicochemical characterization of
molecules. While both IR and Raman spectroscopy have been used for decades to provide …

Light is unsurpassed in its ability to modulate biological interactions. Since their discovery,
chemists have been fascinated by photosensitive molecules capable of switching between …