Introduction: Atopic dermatitis (AD) is the most common inflammatory skin disease. It has a
complex pathophysiology, with a combination of immune dysregulation and intrinsic barrier …

Atopic dermatitis (AD) is a chronic or chronically relapsing, eczematous, severely pruritic
skin disorder associated with skin barrier dysfunction. The lesional skin of AD exhibits T …

Oncostatin M (OSM) and interleukin-31 (IL-31) are two cytokines belonging to the IL-6 family
which share a common signaling receptor subunit, the OSM receptor beta (OSMRβ). Both of …

Several allergic and immunologic diseases including asthma, food allergy (FA), chronic
spontaneous urticaria (CSU), atopic dermatitis (AD), systemic lupus erythematosus (SLE) …

Cytokines play an important role in the regulation of the immune system (adaptive and
innate). Given their importance in proinflammatory processes, cytokines have been used for …

Skin inflammation often evokes pruritus, which is the major subjective symptom in many
inflammatory skin diseases such as atopic dermatitis and prurigo nodularis. Pruritus or itch is …

Asthma is associated with innate and adaptive immunity mediated by immune cells. T cell or
macrophage dysfunction plays a particularly significant role in asthma pathogenesis …

The study of the immunoskeletal interface has led to the discovery of numerous cytokines
involved in the regulation of bone remodeling, providing valuable information on the …

Background: Atopic dermatitis, a chronic inflammatory disease, has a lifetime prevalence of
10–20%. Atopic dermatitis reduces quality of life, primarily due to pruritus. Interleukin-31 and …

Interleukin-31 (IL-31) is a type 2 helper T-cell-derived cytokine that has recently been shown
to cause severe inflammation and tissue remodeling in multiple chronic diseases of the skin …