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Dendritic cells as orchestrators of anticancer immunity and immunotherapy
I Heras-Murillo, I Adán-Barrientos, M Galán… - Nature Reviews …, 2024 - nature.com
Dendritic cells (DCs) are a heterogeneous group of antigen-presenting innate immune cells
that regulate adaptive immunity, including against cancer. Therefore, understanding the …
that regulate adaptive immunity, including against cancer. Therefore, understanding the …
Immune regulation through tryptophan metabolism
SK Seo, B Kwon - Experimental & Molecular Medicine, 2023 - nature.com
Amino acids are fundamental units of molecular components that are essential for sustaining
life; however, their metabolism is closely interconnected to the control systems of cell …
life; however, their metabolism is closely interconnected to the control systems of cell …
Tumor microenvironment remodeling after neoadjuvant immunotherapy in non-small cell lung cancer revealed by single-cell RNA sequencing
J Hu, L Zhang, H ** the systemic tumor immune environment (STIE) and tumor immune microenvironment (TIME) to enhance immunotherapy efficacy in solid tumors
The development of combination immunotherapy based on the mediation of regulatory
mechanisms of the tumor immune microenvironment (TIME) is promising. However, a deep …
mechanisms of the tumor immune microenvironment (TIME) is promising. However, a deep …
Transcriptional signatures associated with persisting CD19 CAR-T cells in children with leukemia
In the context of relapsed and refractory childhood pre-B cell acute lymphoblastic leukemia
(R/R B-ALL), CD19-targeting chimeric antigen receptor (CAR)-T cells often induce durable …
(R/R B-ALL), CD19-targeting chimeric antigen receptor (CAR)-T cells often induce durable …
Single-cell analysis of anti-BCMA CAR T cell therapy in patients with central nervous system autoimmunity
C Qin, M Zhang, DP Mou, LQ Zhou, MH Dong… - Science …, 2024 - science.org
Chimeric antigen receptor (CAR) T cell immunotherapy for the treatment of neurological
autoimmune diseases is promising, but CAR T cell kinetics and immune alterations after …
autoimmune diseases is promising, but CAR T cell kinetics and immune alterations after …
Computational immunogenomic approaches to predict response to cancer immunotherapies
Cancer immunogenomics is an emerging field that bridges genomics and immunology. The
establishment of large-scale genomic collaborative efforts along with the development of …
establishment of large-scale genomic collaborative efforts along with the development of …
Single-cell and spatial transcriptome analyses reveal tertiary lymphoid structures linked to tumour progression and immunotherapy response in nasopharyngeal …
Tertiary lymphoid structures are immune cell aggregates linked with cancer outcomes, but
their interactions with tumour cell aggregates are unclear. Using nasopharyngeal carcinoma …
their interactions with tumour cell aggregates are unclear. Using nasopharyngeal carcinoma …
EBV-associated diseases: Current therapeutics and emerging technologies
EBV is a prevalent virus, infecting> 90% of the world's population. This is an oncogenic virus
that causes~ 200,000 cancer-related deaths annually. It is, in addition, a significant …
that causes~ 200,000 cancer-related deaths annually. It is, in addition, a significant …