Control of mosquito-borne infectious diseases: sex and gene drive

ZN Adelman, Z Tu - Trends in parasitology, 2016 - cell.com
Sterile male releases have successfully reduced local populations of the dengue vector,
Aedes aegypti, but challenges remain in scale and in separating sexes before release. The …

Neuroprotective therapies in glaucoma: II. Genetic nanotechnology tools

N Nafissi, M Foldvari - Frontiers in neuroscience, 2015 - frontiersin.org
Neurotrophic factor genome engineering could have many potential applications not only in
the deeper understanding of neurodegenerative disorders but also in improved …

Mosquito transposon-mediated transgenesis

V Bottino-Rojas, AA James - Cold Spring Harbor Protocols, 2024 - cshprotocols.cshlp.org
Transposon-mediated transgenesis of mosquito vectors of disease pathogens followed the
early success of transgenesis in the vinegar fly, Drosophila melanogaster. The P …

Identification and characterization of highly active promoters from the fall armyworm, Spodoptera frugiperda

X Chen, SCRR Chereddy, D Gurusamy… - Insect Biochemistry and …, 2020 - Elsevier
The cell lines derived from the fall armyworm (FAW), Spodoptera frugiperda, have been
widely used for production of recombinant proteins for applications in both basic research …

Genomic evidence of population genetic differentiation in deep-sea squat lobster Shinkaia crosnieri (crustacea: Decapoda: Anomura) from Northwestern Pacific …

J Cheng, M Hui, Y Li, Z Sha - Deep Sea Research Part I: Oceanographic …, 2020 - Elsevier
The galatheid squat lobster, Shinkaia crosnieri Baba and Williams, 1998, is one of the few
dominant species inhabiting both deep-sea hydrothermal vents and cold seeps. Here, we …

[HTML][HTML] nanos-Driven expression of piggyBac transposase induces mobilization of a synthetic autonomous transposon in the malaria vector mosquito, Anopheles …

VM Macias, AJ Jimenez, B Burini-Ko**… - Insect biochemistry and …, 2017 - Elsevier
Transposons are a class of selfish DNA elements that can mobilize within a genome. If
mobilization is accompanied by an increase in copy number (replicative transposition), the …

Engineering an αCD206-synNotch Receptor: Insights into the Development of Novel Synthetic Receptors

S Semeniuk, BZ Qian, E Cachat - ACS Synthetic Biology, 2024 - ACS Publications
Immune cells play a pivotal role in the establishment, growth, and progression of tumors at
primary and metastatic sites. Macrophages, in particular, play a critical role in suppressing …

The sex locus is tightly linked to factors conferring sex-specific lethal effects in the mosquito Aedes aegypti

E Krzywinska, V Kokoza, M Morris… - Heredity, 2016 - nature.com
In many taxa, sex chromosomes are heteromorphic and largely non-recombining.
Evolutionary models predict that spread of recombination suppression on the Y …

Molecular tools to create new strains for mosquito sexing and vector control

I Häcker, MF Schetelig - Parasites & vectors, 2018 - Springer
Vector control programs based on population reduction by matings with mass-released
sterile insects require the release of only male mosquitoes, as the release of females, even if …

Intravenous Delivery of piggyBac Transposons as a Useful Tool for Liver-Specific Gene-Switching

S Nakamura, M Ishihara, S Watanabe, N Ando… - International journal of …, 2018 - mdpi.com
Hydrodynamics-based gene delivery (HGD) is an efficient method for transfecting plasmid
DNA into hepatocytes in vivo. However, the resulting gene expression is transient, and …